Axonal growth cones mediate axonal guidance and growth regulation. We show that
migrating neurons in mice possess a growth cone at the tip of their leading process, similar …

Spinal cord injury (SCI) often results in various long-term sequelae, and chronically injured
spinal cords exhibit a refractory feature, showing a limited response to cell transplantation …

Estrogen plays fundamental roles in nervous system development and function. Traditional
studies examining the effect of estrogen in the brain have focused on the nuclear estrogen …

Simple Summary Given the significant costs and lengthy timelines of drug development and
clinical trials, drug repositioning is a promising alternative to find effective treatments for …

Spinal cord injury affects the lives of millions of people around the world, often causing
disability and, in unfortunate circumstances, death. Rehabilitation can partly improve …

Background Spinal cord injury (SCI) is a debilitating illness in humans that causes
permanent loss of movement or sensation. To treat SCI, exosomes, with their unique …

Ischemic stroke is a major cerebrovascular disease with high morbidity and mortality rates;
however, effective treatments for ischemic stroke-related neurological dysfunction have yet …

Mammalian axon growth has mechanistic similarities with axon regeneration. The growth
cone is an important structure that is involved in both processes, and GAP-43 (growth …

A growth cone is a highly motile tip of an extending axon that is crucial for neural network
formation. Three‐dimensional‐structured illumination microscopy, a type of super‐resolution …

Parkinson's disease (PD) is a severe neurological disease for which there is no effective
treatment or cure, and therefore it remains an unmet need in medicine. We present data from …