[HTML][HTML] Long walk to genomics: History and current approaches to genome sequencing and assembly
Genomes represent the starting point of genetic studies. Since the discovery of DNA
structure, scientists have devoted great efforts to determine their sequence in an exact way …
structure, scientists have devoted great efforts to determine their sequence in an exact way …
Piercing the dark matter: bioinformatics of long-range sequencing and mapping
Several new genomics technologies have become available that offer long-read sequencing
or long-range mapping with higher throughput and higher resolution analysis than ever …
or long-range mapping with higher throughput and higher resolution analysis than ever …
[HTML][HTML] A complete telomere-to-telomere assembly of the maize genome
J Chen, Z Wang, K Tan, W Huang, J Shi, T Li, J Hu… - Nature …, 2023 - nature.com
A complete telomere-to-telomere (T2T) finished genome has been the long pursuit of
genomic research. Through generating deep coverage ultralong Oxford Nanopore …
genomic research. Through generating deep coverage ultralong Oxford Nanopore …
Convergent selection of a WD40 protein that enhances grain yield in maize and rice
W Chen, L Chen, X Zhang, N Yang, J Guo, M Wang… - Science, 2022 - science.org
A better understanding of the extent of convergent selection among crops could greatly
improve breeding programs. We found that the quantitative trait locus KRN2 in maize and its …
improve breeding programs. We found that the quantitative trait locus KRN2 in maize and its …
[HTML][HTML] Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet
Pearl millet is an important cereal crop worldwide and shows superior heat tolerance. Here,
we developed a graph-based pan-genome by assembling ten chromosomal genomes with …
we developed a graph-based pan-genome by assembling ten chromosomal genomes with …
[HTML][HTML] A graph-based genome and pan-genome variation of the model plant Setaria
Setaria italica (foxtail millet), a founder crop of East Asian agriculture, is a model plant for C4
photosynthesis and developing approaches to adaptive breeding across multiple climates …
photosynthesis and developing approaches to adaptive breeding across multiple climates …
De novo assembly, annotation, and comparative analysis of 26 diverse maize genomes
We report de novo genome assemblies, transcriptomes, annotations, and methylomes for
the 26 inbreds that serve as the founders for the maize nested association mapping …
the 26 inbreds that serve as the founders for the maize nested association mapping …
Liftoff: accurate mapping of gene annotations
A Shumate, SL Salzberg - Bioinformatics, 2021 - academic.oup.com
Motivation Improvements in DNA sequencing technology and computational methods have
led to a substantial increase in the creation of high-quality genome assemblies of many …
led to a substantial increase in the creation of high-quality genome assemblies of many …
[HTML][HTML] Improved pea reference genome and pan-genome highlight genomic features and evolutionary characteristics
Complete and accurate reference genomes and annotations provide fundamental resources
for functional genomics and crop breeding. Here we report a de novo assembly and …
for functional genomics and crop breeding. Here we report a de novo assembly and …
An efficient CRISPR–Cas12a promoter editing system for crop improvement
J Zhou, G Liu, Y Zhao, R Zhang, X Tang, L Li, X Jia… - Nature Plants, 2023 - nature.com
Promoter editing represents an innovative approach to introduce quantitative trait variation
(QTV) in crops. However, an efficient promoter editing system for QTV needs to be …
(QTV) in crops. However, an efficient promoter editing system for QTV needs to be …