Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which
the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether …

Peroxisomes are dynamic organelles that play an essential role in a variety of cellular
catabolic and anabolic metabolic pathways, including fatty acid alpha-and beta-oxidation …

Myelin is a specialized cell membrane indispensable for rapid nerve conduction. The high
abundance of membrane lipids is one of myelin's salient features that contribute to its unique …

Peroxisomes contain numerous enzymatic activities that are important for mammalian
physiology. Patients lacking either all peroxisomal functions or a single enzyme or …

The emerging diverse roles of ether (phospho) lipids in nervous system development and
function in health and disease are currently attracting growing interest. Plasmalogens, a …

Inborn errors of metabolism, also known as inherited metabolic diseases, constitute an
important group of conditions presenting with neurologic signs in newborns. They are …

Background Acyl-CoA binding domain containing protein 5 (ACBD5) is a peroxisomal
membrane protein with a cytosolic acyl-CoA binding domain. Because of its acyl-CoA …

Plasmalogens, mostly ethanolamine‐containing alkenyl ether phospholipids, are a major
subclass of glycerophospholipids. Plasmalogen synthesis is initiated in peroxisomes and …

Autophagy is an intracellular degradation pathway for large protein aggregates and
damaged organelles. Recent studies have indicated that autophagy targets cargoes through …