Simple Summary In mammals, circadian rhythms in nearly all behaviors and physiological
processes are controlled by the suprachiasmatic nucleus, a collection of neurons in the …

Depression has become one of the most commonly prevalent neuropsychiatric disorders,
and the main characteristics of depression are sleep disorders and melatonin secretion …

The production of plastic is still increasing globally, which has led to an increasing number
of plastic particles in the environment. Nanoplastics (NPs) can penetrate the blood-brain …

Melatonin, an indole produced by pineal and extrapineal tissues, but also taken with a
vegetarian diet, has strong anti-oxidant, anti-inflammatory and anti-obesogenic potentials …

Abstract Circadian (24-h) clocks are cell-autonomous biological oscillators that orchestrate
many aspects of our physiology on a daily basis. Numerous circadian rhythms in …

Circadian timekeeping mechanisms and cell cycle regulation share thematic biological
principles in responding to signals, repairing cellular damage, coordinating metabolism, and …

There continues to be considerable interest in the physiological role (s) of the hormone
melatonin and its potential as a drug more than 60 years after its discovery. While there is an …

Anorexia nervosa (AN) is characterized by emaciation, hyperactivity, and amenorrhea. To
what extent AN-related symptoms are due to food restriction or neuronal dysfunction is …

The mammalian retina is the most unique tissue among those that display robust
circadian/diurnal oscillations. The retina is not only a light sensing tissue that relays light …

The hormone melatonin is synthesized from serotonin by two enzymatic reactions (AANAT
and ASMT/HIOMT) in the pineal gland following a circadian rhythm with low levels during …