Vitellogenins - Yolk Gene Function and Regulation in Caenorhabditis elegans
Vitellogenins are a family of yolk proteins that are by far the most abundant among
oviparous animals. In the model nematode Caenorhabditis elegans, the 6 vitellogenins are …
oviparous animals. In the model nematode Caenorhabditis elegans, the 6 vitellogenins are …
[HTML][HTML] Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
Distinguishing infectious pathogens from harmless microorganisms is essential for animal
health. The mechanisms used to identify infectious microbes are not fully understood …
health. The mechanisms used to identify infectious microbes are not fully understood …
Immunometabolism in Caenorhabditis elegans
SM Anderson, R Pukkila-Worley - PLoS pathogens, 2020 - journals.plos.org
Host metabolism is profoundly altered during bacterial infection, both as a consequence of
immune activation and secondary to virulence strategies of invading pathogens. As a result …
immune activation and secondary to virulence strategies of invading pathogens. As a result …
An intestinal sphingolipid confers intergenerational neuroprotection
W Wang, T Sherry, X Cheng, Q Fan, R Cornell… - Nature Cell …, 2023 - nature.com
In animals, maternal diet and environment can influence the health of offspring. Whether and
how maternal dietary choice impacts the nervous system across multiple generations is not …
how maternal dietary choice impacts the nervous system across multiple generations is not …
Opposing action of the FLR-2 glycoprotein hormone and DRL-1/FLR-4 MAP kinases balance p38-mediated growth and lipid homeostasis in C. elegans
SK Torzone, AY Park, PC Breen, NR Cohen… - PLoS …, 2023 - journals.plos.org
Animals integrate developmental and nutritional signals before committing crucial resources
to growth and reproduction; however, the pathways that perceive and respond to these …
to growth and reproduction; however, the pathways that perceive and respond to these …
Kombucha Tea-associated microbes remodel host metabolic pathways to suppress lipid accumulation
RN DuMez-Kornegay, LS Baker, AJ Morris… - Plos …, 2024 - journals.plos.org
The popularity of the ancient, probiotic-rich beverage Kombucha Tea (KT) has surged in part
due to its purported health benefits, which include protection against metabolic diseases; …
due to its purported health benefits, which include protection against metabolic diseases; …
Maintenance of quiescent oocytes by noradrenergic signals
All females adopt an evolutionary conserved reproduction strategy; under unfavorable
conditions such as scarcity of food or mates, oocytes remain quiescent. However, the signals …
conditions such as scarcity of food or mates, oocytes remain quiescent. However, the signals …
The molecular tug of war between immunity and fertility: emergence of conserved signaling pathways and regulatory mechanisms
N Naim, FRG Amrit, TB McClendon, JL Yanowitz… - …, 2020 - Wiley Online Library
Reproduction and immunity are energy intensive, intimately linked processes in most
organisms. In women, pregnancy is associated with widespread immunological adaptations …
organisms. In women, pregnancy is associated with widespread immunological adaptations …
PQM-1 controls hypoxic survival via regulation of lipid metabolism
Animals have evolved responses to low oxygen conditions to ensure their survival. Here, we
have identified the C. elegans zinc finger transcription factor PQM-1 as a regulator of the …
have identified the C. elegans zinc finger transcription factor PQM-1 as a regulator of the …
Endomitosis controls tissue-specific gene expression during development
LM van Rijnberk, R Barrull-Mascaró… - PLoS …, 2022 - journals.plos.org
Polyploid cells contain more than 2 copies of the genome and are found in many plant and
animal tissues. Different types of polyploidy exist, in which the genome is confined to either 1 …
animal tissues. Different types of polyploidy exist, in which the genome is confined to either 1 …