[HTML][HTML] Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics
T Nojima, NJ Proudfoot - Nature reviews Molecular cell biology, 2022 - nature.com
Mammalian genomes express two principal gene categories through RNA polymerase II-
mediated transcription: protein-coding transcription units and non-coding RNA transcription …
mediated transcription: protein-coding transcription units and non-coding RNA transcription …
The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis
A Shilatifard - Annual review of biochemistry, 2012 - annualreviews.org
The Saccharomyces cerevisiae Set1/COMPASS was the first histone H3 lysine 4 (H3K4)
methylase identified over 10 years ago. Since then, it has been demonstrated that …
methylase identified over 10 years ago. Since then, it has been demonstrated that …
The RNA polymerase II CTD coordinates transcription and RNA processing
The C-terminal domain (CTD) of the RNA polymerase II largest subunit consists of multiple
heptad repeats (consensus Tyr1–Ser2–Pro3–Thr4–Ser5–Pro6–Ser7), varying in number …
heptad repeats (consensus Tyr1–Ser2–Pro3–Thr4–Ser5–Pro6–Ser7), varying in number …
Small nucleolar RNAs tell a different tale
J Kufel, P Grzechnik - Trends in Genetics, 2019 - cell.com
Transcribing RNA Polymerase II interacts with multiple factors that orchestrate maturation
and stabilisation of messenger RNA. For the majority of noncoding RNAs, the polymerase …
and stabilisation of messenger RNA. For the majority of noncoding RNAs, the polymerase …
[HTML][HTML] The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II
The carboxy-terminal domain (CTD) of the RNA polymerase II (RNApII) largest subunit
consists of multiple heptapeptide repeats with the consensus sequence YSPTSPS. Different …
consists of multiple heptapeptide repeats with the consensus sequence YSPTSPS. Different …
[HTML][HTML] Unravelling the means to an end: RNA polymerase II transcription termination
JN Kuehner, EL Pearson, C Moore - Nature reviews Molecular cell …, 2011 - nature.com
The pervasiveness of RNA synthesis in eukaryotes is largely the result of RNA polymerase II
(Pol II)-mediated transcription, and termination of its activity is necessary to partition the …
(Pol II)-mediated transcription, and termination of its activity is necessary to partition the …
Glucose Signaling in Saccharomyces cerevisiae
GM Santangelo - Microbiology and Molecular Biology Reviews, 2006 - Am Soc Microbiol
Eukaryotic cells possess an exquisitely interwoven and fine-tuned series of signal
transduction mechanisms with which to sense and respond to the ubiquitous fermentable …
transduction mechanisms with which to sense and respond to the ubiquitous fermentable …
The Paf1 complex: a keystone of nuclear regulation operating at the interface of transcription and chromatin
The regulation of transcription by RNA polymerase II is closely intertwined with the
regulation of chromatin structure. A host of proteins required for the disassembly …
regulation of chromatin structure. A host of proteins required for the disassembly …
Transcription termination by nuclear RNA polymerases
P Richard, JL Manley - Genes & development, 2009 - genesdev.cshlp.org
Gene transcription in the cell nucleus is a complex and highly regulated process.
Transcription in eukaryotes requires three distinct RNA polymerases, each of which employs …
Transcription in eukaryotes requires three distinct RNA polymerases, each of which employs …
[HTML][HTML] Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS
JS Lee, A Shukla, J Schneider, SK Swanson… - Cell, 2007 - cell.com
COMPASS, the yeast homolog of the mammalian MLL complex, is a histone H3 lysine 4
(H3K4) methylase consisting of Set1 (KMT2) and seven other polypeptides, including …
(H3K4) methylase consisting of Set1 (KMT2) and seven other polypeptides, including …