Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria
RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
C/EBPβ-dependent epigenetic memory induces trained immunity in hematopoietic stem cells
B de Laval, J Maurizio, PK Kandalla, G Brisou… - Cell stem cell, 2020 - cell.com
Hematopoietic stem cells (HSCs) maintain life-long production of immune cells and can
directly respond to infection, but sustained effects on the immune response remain unclear …
directly respond to infection, but sustained effects on the immune response remain unclear …
Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?
Hosts and bacteria have coevolved over millions of years, during which pathogenic bacteria
have modified their virulence mechanisms to adapt to host defense systems. Although the …
have modified their virulence mechanisms to adapt to host defense systems. Although the …
Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence
Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …
Pseudomonas biofilm matrix composition and niche biology
EE Mann, DJ Wozniak - FEMS microbiology reviews, 2012 - academic.oup.com
Biofilms are a predominant form of growth for bacteria in the environment and in the clinic.
Critical for biofilm development are adherence, proliferation, and dispersion phases. Each of …
Critical for biofilm development are adherence, proliferation, and dispersion phases. Each of …
Biofilm Matrix and Its Regulation in Pseudomonas aeruginosa
Q Wei, LZ Ma - International journal of molecular sciences, 2013 - mdpi.com
Biofilms are communities of microorganisms embedded in extracellular polymeric
substances (EPS) matrix. Bacteria in biofilms demonstrate distinct features from their free …
substances (EPS) matrix. Bacteria in biofilms demonstrate distinct features from their free …
Two-component systems required for virulence in Pseudomonas aeruginosa
VI Francis, EC Stevenson, SL Porter - FEMS microbiology letters, 2017 - academic.oup.com
Pseudomonas aeruginosa is a versatile opportunistic pathogen capable of infecting a broad
range of hosts, in addition to thriving in a broad range of environmental conditions outside of …
range of hosts, in addition to thriving in a broad range of environmental conditions outside of …
The Pseudomonas aeruginosa opportunistic pathogen and human infections
S De Bentzmann, P Plésiat - Environmental microbiology, 2011 - Wiley Online Library
Pseudomonas aeruginosa, a Gram‐negative environmental species and an opportunistic
microorganism, establishes itself in vulnerable patients, such as those with cystic fibrosis or …
microorganism, establishes itself in vulnerable patients, such as those with cystic fibrosis or …
Roles of two-component regulatory systems in antibiotic resistance
ARP Tierney, PN Rather - Future microbiology, 2019 - Taylor & Francis
Two-component regulatory systems (TCSs) are a major mechanism by which bacteria sense
and respond to changes in their environment. TCSs typically consist of two proteins that …
and respond to changes in their environment. TCSs typically consist of two proteins that …