Hydrophilic drugs are proficient therapeutic agents however, delivery of these drugs is a
difficult task. Hence, developing an efficient drug delivery system may require a …

Cancer represents a group of heterogeneous diseases characterized by uncontrolled
growth and spread of abnormal cells, ultimately leading to death. Nanomedicine plays a …

Multidrug resistance (MDR) is a major cause of failure in cancer chemotherapy. P-
glycoprotein (P-gp), a promiscuous drug efflux pump, has been extensively studied for its …

Chemotherapy, a major strategy for cancer treatment, lacks the specificity to localize the
cancer therapeutics in the tumor site, thereby affecting normal healthy tissues and …

The delivery of drugs through targeted nanocarriers that are internalized by cells provides
an alternative route to diffusion of drugs into cells. Growth factor or vitamin interactions with …

This review article is an updated overview on lipid-polymer hybrid nanoparticles (LPHNs)
including the various types of LPHNs polymers used in their preparation, various methods of …

Solid lipid nanoparticles are at the forefront of the rapidly developing field of nanotechnology
with several potential applications in drug delivery, clinical medicine and research, as well …

The core objective of nanoparticles is to control and manipulate biomacromolecular
constructs and supramolecular assemblies that are critical to living cells in order to improve …

The focus of nanoparticle design over the years has evolved toward more complex
nanoscopic core–shell architecture using a single delivery system to combine multiple …

In the United States, the estimated number of new cancer cases in 2018 will be approx. 1.7
million. Historically, combination chemotherapy has been the primary choice of treatment …