Classical celiac disease is more frequent with a double dose of HLA-DQB1* 02: A systematic review with meta-analysis

J Bajor, Z Szakács, N Farkas, P Hegyi, A Illés… - PLoS …, 2019 - journals.plos.org
Background and aims Experimental data suggest that the HLA-DQ2 gene dose has a strong
quantitative effect on clinical outcomes and severity of celiac disease (CD). We aimed to …

HLA-DQ genetics in children with celiac disease: a meta-analysis suggesting a two-step genetic screening procedure starting with HLA-DQ β chains

A De Silvestri, C Capittini, D Poddighe, C Valsecchi… - Pediatric …, 2018 - nature.com
Background Specific HLA-DQ genes have been recognized as necessary-but not sufficient-
factors for the occurrence of Celiac Disease (CD). Through a meta-analysis, evaluating the …

HLA-DQ2/8 and COVID-19 in celiac disease: Boon or Bane

A Lerner, C Benzvi, A Vojdani - Microorganisms, 2023 - mdpi.com
The SARS-CoV-2 pandemic continues to pose a global threat. While its virulence has
subsided, it has persisted due to the continual emergence of new mutations. Although many …

Immunogenetics of Celiac Disease: A focus on Arab countries

N Younes, S Younes, O Alsharabasi… - Current molecular …, 2020 - ingentaconnect.com
Celiac Disease (CD) is a complex immunogenic disease mainly triggered by gluten intake in
genetically susceptible individuals with a prevalence of 1 in 100-300. CD results from the …

HLA‐DQ genotypes relative risks for celiac disease in Arabs: A case‐control study

A Al‐Hussaini, N Eltayeb‐Elsheikh… - Journal of digestive …, 2019 - Wiley Online Library
Objectives It remains unknown what degree of risk is conferred by celiac disease (CD)‐
predisposing human leukocyte antigen (HLA)‐DQ genotypes in Saudi Arabia compared with …

[PDF][PDF] The influence of HLA-DQ2 heterodimers on the clinical features and laboratory of patients with celiac disease

HH Akar, M Yıldız, E Sevinc, S Sokucu - Nutricion Hospitalaria, 2015 - redalyc.org
Background and aim: the essential genetic marker re-lated with celiac disease (CD) is the
HLA-DQ2 molecule encoded by the DQA1* 0501 and DQB1* 0201 genes. The aim of this …

Selected human leukocyte antigen class II polymorphisms and risk of adult glioma

BA Bassig, PD Inskip, L Burdette, WR Shapiro… - Journal of …, 2011 - Elsevier
Few studies have examined the relationship between human leukocyte antigen (HLA)
polymorphisms and adult glioma, particularly at class II loci. We evaluated the association …

[PDF][PDF] Association of celiac disease with HLA-DRB1 and HLADQB1 alleles in a sample of Iraqi paients

H Abdullah, A Thawani - Iraqi J. Biotech, 2012 - iasj.net
Celiac disease (CD) is a complex disorder triggered by gluten affecting genetically
predisposed individuals. The CD is triggered by the binding of one or more gliadin peptides …

HLA 1-го и 2-го классов при целиакии у жителей Беларуси

ЮВ Горгун, ГВ Семенов, АС Портянко - Клиническая медицина, 2010 - elibrary.ru
Целиакия-генетически детерминированное заболевание, в развитии которого
ключевую роль играют HLA-гены. Цель исследования заключалась в оценке HLA …

[PDF][PDF] A HLA genotípus szerepe a coeliakia klinikai képének alakításában

B Judit - 2020 - pea.lib.pte.hu
A coeliakia (gluténszenzitív enteropathia, nem trópusi sprue, lisztérzékenység) genetikailag
fogékony egyénben glutén hatására kialakuló szisztémás autoimmun betegség, mely …