Conceptus signals for establishment and maintenance of pregnancy

TE Spencer, FW Bazer - Reproductive Biology and Endocrinology, 2004 - Springer
Establishment and maintenance of pregnancy results from signaling by the conceptus
(embryo/fetus and associated extraembryonic membranes) and requires progesterone …

[PDF][PDF] Biology of progesterone action during pregnancy recognition and maintenance of pregnancy

TE Spencer, FW Bazer - Front Biosci, 2002 - article.imrpress.com
[Frontiers in Bioscience 7, d1879-1898, September 1, 2002] 1879 BIOLOGY OF
PROGESTERONE ACTION DURING PREGNANCY RECOGNITION AND Page 1 [Frontiers in …

Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium

MY Turco, L Gardner, J Hughes, T Cindrova-Davies… - Nature cell …, 2017 - nature.com
In humans, the endometrium, the uterine mucosal lining, undergoes dynamic changes
throughout the menstrual cycle and pregnancy. Despite the importance of the endometrium …

Progesterone and placental hormone actions on the uterus: insights from domestic animals

TE Spencer, GA Johnson, RC Burghardt… - Biology of …, 2004 - academic.oup.com
Progesterone is unequivocally required for maternal support of conceptus (embryo/fetus and
associated extraembryonic membranes) survival and development. In cyclic sheep …

Conceptus-induced changes in the endometrial transcriptome: how soon does the cow know she is pregnant?

N Forde, F Carter, TE Spencer, FW Bazer… - Biology of …, 2011 - academic.oup.com
This study sought to determine the earliest response of the bovine uterine endometrium to
the presence of the conceptus at key developmental stages of early pregnancy. There were …

Interferons and progesterone for establishment and maintenance of pregnancy: interactions among novel cell signaling pathways

FW Bazer, RC Burghardt, GA Johnson, TE Spencer… - Reproductive …, 2008 - Elsevier
Type I and/or type II interferons (IFNs) are important in establishing uterine receptivity to
implantation in mammals. Gene expression effected by IFNs may be induced, stimulated or …

Uterine biology in pigs and sheep

FW Bazer, G Song, J Kim, KA Dunlap… - Journal of animal …, 2012 - Springer
There is a dialogue between the developing conceptus (embryo-fetus and associated
placental membranes) and maternal uterus which must be established during the peri …

Keratinocyte growth factor is up-regulated by estrogen in the porcine uterine endometrium and functions in trophectoderm cell proliferation and differentiation

H Ka, LA Jaeger, GA Johnson, TE Spencer… - …, 2001 - academic.oup.com
Keratinocyte growth factor (KGF) is expressed by uterine endometrial epithelial cells during
the estrous cycle and during pregnancy in pigs, whereas KGF receptor is expressed in …

Mechanisms for the establishment and maintenance of pregnancy: synergies from scientific collaborations

FW Bazer, RC Burghardt, GA Johnson… - Biology of …, 2018 - academic.oup.com
Research on the functions of interferon tau (IFNT) led to the theory of pregnancy recognition
signaling in ruminant species. But IFNT does much more as it induces expression of …

Vascular endothelial growth factor, epidermal growth factor and fibroblast growth factor‐4 and‐10 stimulate trophoblast plasminogen activator system and …

EY Anteby, C Greenfield… - Molecular human …, 2004 - academic.oup.com
Trophoblast invasion, accompanied by degradation of extracellular matrix, is crucial to
normal pregnancy development, whereas shallow placental invasion and implantation likely …