On 2 February 2024, the Pan American Health Organization/World Health Organization
issued an epidemiological alert on rising Oropouche virus (OROV) infections in South …

Since its discovery in 1955, the incidence and geographical spread of reported Oropouche
virus (OROV) infections have increased. Oropouche fever has been suggested to be one of …

Background Oropouche fever, an orthobunyavirus disease endemic in Brazilian Amazon,
has caused many febrile epidemics. In 2024, an epidemic of Oropouche fever spread in …

Viral neuroinfections represent a major health burden for which the development of
antivirals is needed. Antiviral compounds that target the consequences of a brain infection …

Advances in translational neuroscience require experimental models recapitulating the
complexity of the human brain. In contrast to conventional 2D cell culture models and animal …

Oropouche virus (OROV) is an arbovirus transmitted by midges that is now emerging outside
the Amazon region. For the first time, fatal cases were reported, and possible vertical …

Many viral infections cause acute and chronic neurologic diseases which can lead to
degeneration of cortical functions. While neurotropic viruses that gain access to the central …

The Oropouche virus is an important arthropod-borne virus in the Peribunyaviridae family
that can cause febrile illnesses, and it is widely distributed in tropical regions such as …

Since the intricate and complex steps in pathogenesis and host-viral interactions of
arthropod-borne viruses or arboviruses are not completely understood, the multi-omics …

Human retroelements (HERVs) are retroviral origin sequences fixed in the human genome.
HERVs induction is associated with neurogenesis, cellular development, immune activation …