Numerous drug treatments that have recently entered the clinic or clinical trials have their
genesis in zebrafish. Zebrafish are well established for their contribution to developmental …

Unpredicted human safety events in clinical trials for new drugs are costly in terms of human
health and money. The drug discovery industry attempts to minimize those events with …

This article provides recommendations for the care of laboratory zebrafish (Danio rerio) as
part of the further implementation of Annex A to the European Convention on the protection …

Background The posttranscriptional modifications of transfer RNA (tRNA) are critical for all
aspects of the tRNA function and have been implicated in the tumourigenesis and …

The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Obesity and diabetes now considered global epidemics. The prevalence rates of diabetes
are increasing in parallel with the rates of obesity and the strong connection between these …

To discover new molecules or review the biological activity and toxicity of therapeutic
substances, drug development, and research relies on robust biological systems to obtain …

Hematopoietic stem cells (HSCs) possess two important properties such as self-renewal and
differentiation. These properties of HSCs are maintained through hematopoiesis. This …

Photocatalytic anticancer profile of a IrIII photocatalyst (Ir3) with strong light absorption, high
turnover frequency, and excellent biocompatibility is reported. Ir3 showed selective photo …

The laboratory zebrafish (Danio rerio) is now an accepted model in toxicologic research.
The zebrafish model fills a niche between in vitro models and mammalian biomedical …