New molecular and biochemical insights of doxorubicin-induced hepatotoxicity

PL Prasanna, K Renu, AV Gopalakrishnan - Life sciences, 2020 - Elsevier
Chemotherapeutic antibiotic doxorubicin belongs to the anthracycline class, slaughters not
only the cancer cells but also non-cancerous cells even in the non-targeted organs thereby …

[HTML][HTML] Antioxidant therapy for treatment of inflammatory bowel disease: does it work?

FA Moura, KQ de Andrade, JCF Dos Santos… - Redox biology, 2015 - Elsevier
Oxidative stress (OS) is considered as one of the etiologic factors involved in several signals
and symptoms of inflammatory bowel diseases (IBD) that include diarrhea, toxic megacolon …

Ferroptosis involves in intestinal epithelial cell death in ulcerative colitis

M Xu, J Tao, Y Yang, S Tan, H Liu, J Jiang… - Cell Death & …, 2020 - nature.com
Ferroptosis has recently emerged as an iron-dependent form of nonapoptotic cell death,
which is also a regulated necrosis process and a response to tumor suppression. However …

The implications of oxidative stress and antioxidant therapies in Inflammatory Bowel Disease: Clinical aspects and animal models

IM Balmus, A Ciobica, A Trifan… - Saudi journal of …, 2016 - journals.lww.com
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), is a chronic inflammatory disorder characterized by alternating phases of clinical …

The role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases

A Piechota-Polanczyk, J Fichna - Naunyn-Schmiedeberg's archives of …, 2014 - Springer
In this review, we focus on the role of oxidative stress in the aetiology of inflammatory bowel
diseases (IBD) and colitis-associated colorectal cancer and discuss free radicals and free …

Prussian blue nanozyme with multienzyme activity reduces colitis in mice

J Zhao, X Cai, W Gao, L Zhang, D Zou… - … applied materials & …, 2018 - ACS Publications
The overproduction of reactive oxygen species (ROS) is central to the progression of
inflammatory bowel disease (IBD), which may be the potential therapeutic target. Prussian …

Extracellular vesicles derived from bone marrow mesenchymal stem cells protect against experimental colitis via attenuating colon inflammation, oxidative stress and …

J Yang, XX Liu, H Fan, Q Tang, ZX Shou, DM Zuo… - PloS one, 2015 - journals.plos.org
The administration of bone mesenchymal stem cells (BMSCs) could reverse experimental
colitis, and the predominant mechanism in tissue repair seems to be related to their …

[HTML][HTML] Influence of body condition score on relationships between metabolic status and oxidative stress in periparturient dairy cows

U Bernabucci, B Ronchi, N Lacetera, A Nardone - Journal of dairy science, 2005 - Elsevier
Twenty-four dairy cows were monitored during the transition period. We observed changes
of oxidative status and relationships between oxidative and metabolic status. Body condition …

Pancreatic stellate cells: a starring role in normal and diseased pancreas

MV Apte, RC Pirola, JS Wilson - Frontiers in physiology, 2012 - frontiersin.org
While the morphology and function of cells of the exocrine and endocrine pancreas have
been studied over several centuries, one important cell type in the gland, the pancreatic …

[HTML][HTML] Pancreatic stellate cell: Pandora's box for pancreatic disease biology

RR Bynigeri, A Jakkampudi, R Jangala… - World journal of …, 2017 - ncbi.nlm.nih.gov
Pancreatic stellate cells (PSCs) were identified in the early 1980s, but received much
attention after 1998 when the methods to isolate and culture them from murine and human …