Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

The tumor development and metastasis are closely related to the structure and function of
the tumor microenvironment (TME). Recently, TME modulation strategies have attracted …

The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing
and treating patients. Nanomaterials are promising vehicles to transport agents that include …

Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

Abstract The Enhanced Permeability and Retention (EPR) effect has been recognized as the
central paradigm in tumor-targeted delivery in the last decades. In the wake of this concept …

The tumor-associated vasculature imposes major structural and biochemical barriers to the
infiltration of effector T cells and effective tumor control. Correlations between stimulator of …

Cancer is a disease which frequently has a poor prognosis. Although multiple therapeutic
strategies have been developed for various cancers, including chemotherapy, radiotherapy …

The tumour microenvironment (TME) constitutes the area surrounding the tumour during its
development and has been demonstrated to play roles in cancer-related diseases through …

Starting with the enhanced permeability and retention (EPR) effect discovery, nanomedicine
has gained a crucial role in cancer treatment. The advances in the field have led to the …

Nanotechnology-based drug delivery platforms have been explored for cancer treatments
and resulted in several nanomedicines in clinical uses and many in clinical trials. However …