Epicardial adipose tissue in contemporary cardiology

G Iacobellis - Nature reviews cardiology, 2022 - nature.com
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …

Local and systemic effects of the multifaceted epicardial adipose tissue depot

G Iacobellis - Nature Reviews Endocrinology, 2015 - nature.com
Epicardial adipose tissue is a unique and multifaceted fat depot with local and systemic
effects. This tissue is distinguished from other visceral fat depots by a number of anatomical …

Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue

SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Childhood obesity and cardiovascular dysfunction

AT Cote, KC Harris, C Panagiotopoulos… - Journal of the American …, 2013 - jacc.org
Obesity-related cardiovascular disease in children is becoming more prevalent in
conjunction with the rise in childhood obesity. Children with obesity are predisposed to an …

Epicardial adipose tissue: clinical biomarker of cardio-metabolic risk

AC Villasante Fricke, G Iacobellis - International journal of molecular …, 2019 - mdpi.com
Epicardial adipose tissue (EAT) is part of the visceral adipose tissue (VAT) that surrounds
the heart and it is a quantifiable, modifiable, and multifaceted tissue that has both local and …

Epicardial adipose tissue and cardiovascular diseases

AM Ansaldo, F Montecucco, A Sahebkar… - International journal of …, 2019 - Elsevier
Obesity is a heterogeneous disease with different degrees of cardiovascular (CV) and
metabolic manifestations. Certain ectopic fat depots may contribute to obesity-related CV …

Heterogeneity of white adipose tissue: molecular basis and clinical implications

KHM Kwok, KSL Lam, A Xu - Experimental & molecular medicine, 2016 - nature.com
Adipose tissue is a highly heterogeneous endocrine organ. The heterogeneity among
different anatomical depots stems from their intrinsic differences in cellular and physiological …

Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features

G Iacobellis, AC Bianco - Trends in Endocrinology & Metabolism, 2011 - cell.com
Epicardial adipose tissue is an unusual visceral fat depot with anatomical and functional
contiguity to the myocardium and coronary arteries. Under physiological conditions …

Echocardiographic epicardial fat: a review of research and clinical applications

G Iacobellis, HJ Willens - Journal of the American Society of …, 2009 - Elsevier
Epicardial fat plays a role in cardiovascular diseases. Because of its anatomic and functional
proximity to the myocardium and its intense metabolic activity, some interactions between …

Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor?

LS Bhatia, NP Curzen, PC Calder… - European heart …, 2012 - academic.oup.com
Non-alcoholic fatty liver disease (NAFLD) affects up to a third of the population worldwide
and may confer increased cardiometabolic risk with consequent adverse cardiovascular …