Role of regucalcin in maintaining cell homeostasis and function

M Yamaguchi - International journal of molecular …, 2005 - spandidos-publications.com
Regucalcin was discovered in 1978 as a Ca2+-binding protein that does not contain EF-
hand motif of Ca2+-binding domain. The name regucalcin was proposed for this Ca22+ …

Role of regucalcin in calcium signaling

M Yamaguchi - Life sciences, 2000 - Elsevier
Regucalcin was discovered in 1978 as a calcium-binding protein that does not contain EF-
hand motif of Ca2+-binding domain [M. Yamaguchi and T. Yamamoto, Chem. Pharm. Bull …

Validation of putative genomic biomarkers of nephrotoxicity in rats

EJ Wang, RD Snyder, MR Fielden, RJ Smith, YZ Gu - Toxicology, 2008 - Elsevier
Drug-induced renal injury is a common finding in the early preclinical phase of drug
development. But the specific genes responding to renal injury remain poorly defined …

Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase

T Sasaki, S Lian, A Khan, JR Llop, AV Samuelson… - Autophagy, 2017 - Taylor & Francis
ABSTRACT Spns1 (Spinster homolog 1 [Drosophila]) in vertebrates, as well as Spin
(Spinster) in Drosophila, is a hypothetical lysosomal H+-carbohydrate transporter, which …

[HTML][HTML] Regucalcin Is a Potential Regulator in Human Cancer: Aiming to Expand into Cancer Therapy

M Yamaguchi - Cancers, 2023 - mdpi.com
Simple Summary Regucalcin plays a multifunctional role in the regulation of cell function
and expresses a repressive effect in the growth of normal cells. Of note, there is increasing …

Suppression of cell proliferation and deoxyribonucleic acid synthesis in the cloned rat hepatoma H4‐II‐E cells overexpressing regucalcin

H Misawa, S Inagaki… - Journal of cellular …, 2002 - Wiley Online Library
The role of endogenous regucalcin (RC) in the regulation of cell proliferation was
investigated in the cloned rat hepatoma H4‐II‐E cells overexpressing RC stably. H4‐II‐E …

[HTML][HTML] Prediction of sex-determination mechanisms in avian primordial germ cells using RNA-seq analysis

K Ichikawa, Y Nakamura, H Bono, R Ezaki… - Scientific Reports, 2022 - nature.com
In birds, sex is determined through cell-autonomous mechanisms and various factors, such
as the dosage of DMRT1. While the sex-determination mechanism in gonads is well known …

Overexpression of regucalcin suppresses cell death in cloned rat hepatoma H4‐II‐E cells induced by tumor necrosis factor‐α or thapsigargin

T Izumi, M Yamaguchi - Journal of cellular biochemistry, 2004 - Wiley Online Library
The role of regucalcin, which is a regulatory protein in intracellular signaling pathway, in the
regulation of cell death was investigated by using the cloned rat hepatoma H4‐II‐E cells …

Overexpression of regucalcin suppresses cell proliferation in cloned rat hepatoma H4‐II‐E cells: involvement of intracellular signaling factors and cell cycle‐related …

M Yamaguchi, Y Daimon - Journal of cellular biochemistry, 2005 - Wiley Online Library
The role of regucalcin, which is a regulatory protein in intracellular signaling pathway, in the
regulation of cell proliferation was investigated by using the cloned rat hepatoma H4‐II‐E …

Mitochondrial dysfunction and oxidative damage in the liver and kidney of rats following exposure to copper nanoparticles for five consecutive days

R Lei, B Yang, C Wu, M Liao, R Ding… - Toxicology …, 2015 - academic.oup.com
Objective: The goal of the current study was to investigate the molecular mechanisms of
copper nanoparticle (CuNP)-induced hepato-and nephrotoxicity by a proteomic analysis that …