Insights from insulin resistance pathways: therapeutic approaches against Alzheimer associated diabetes mellitus

A Fauzi, ES Thoe, TY Quan, ACY Yin - Journal of Diabetes and its …, 2023 - Elsevier
Abstract Alzheimer Associated Diabetes Mellitus, commonly known as Type 3 Diabetes
Mellitus (T3DM) is a distinct subtype of diabetes with a pronounced association with …

[HTML][HTML] GLP-1 Analogs, SGLT-2, and DPP-4 Inhibitors: A Triad of Hope for Alzheimer's Disease Therapy

M Złotek, A Kurowska, M Herbet, I Piątkowska-Chmiel - Biomedicines, 2023 - mdpi.com
Alzheimer's is a prevalent, progressive neurodegenerative disease marked by cognitive
decline and memory loss. The disease's development involves various pathomechanisms …

MST1 selective inhibitor Xmu-mp-1 ameliorates neuropathological changes in a rat model of sporadic Alzheimer's Disease by modulating Hippo-Wnt signaling …

MR Sahu, MH Ahmad, AC Mondal - Apoptosis, 2024 - Springer
Abstract Alzheimer's disease (AD), the most prevalent form of dementia, is characterized by
progressive cognitive impairment accompanied by aberrant neuronal apoptosis. Reports …

MSC-Derived Extracellular Vesicles Alleviate NLRP3/GSDMD-Mediated Neuroinflammation in Mouse Model of Sporadic Alzheimer's Disease

L Lin, L Huang, S Huang, W Chen, H Huang… - Molecular …, 2024 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease, with sporadic
form being the predominant type. Neuroinflammation plays a critical role in accelerating …

[HTML][HTML] Anti-Inflammatory Effects of Dipeptidyl Peptidase-4 Inhibitors and Their Therapeutic Application for Parkinson's Disease

Y Bang, SH Moon, S Lee, HJ Choi - Drug Targets and Therapeutics, 2024 - journal-dtt.org
Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons,
leading to a decline in dopamine levels and the manifestation of motor and non-motor …

New advances in the treatment of Alzheimer's disease with antidiabetic drugs

J Wang, L Ma, Y Lv - International Journal of Frontiers in …, 2023 - francis-press.com
Alzheimer's disease (AD) is a persistent neurological disorder characterized by increasing
cognitive impairment and is the most prevalent type of dementia. The most common …