Vascular endothelial cells form the inner layer of blood vessels where they have a key role
in the development and maintenance of the functional circulatory system and provide …

LSECs are a unique population of endothelial cells within the liver and are recognized as
key regulators of liver homeostasis. LSECs also play a key role in liver disease, as …

Non-alcoholic fatty liver disease (NAFLD) is considered as the hepatic manifestation of
metabolic syndrome, which is characterised by obesity, insulin resistance …

The evolution of the vertebrate liver is a prime example of the evolution of complex organs,
yet the driving genetic factors behind it remain unknown. Here we study the evolutionary …

The metabolic, digestive and homeostatic roles of the liver are dependent on proper
crosstalk and organization of hepatic cell lineages. These hepatic cell lineages are derived …

The haemostatic system involves an array of circulating coagulation factors, which work in
concert with platelets and the vascular endothelium to promote clotting in a space and time …

Vascular endothelial cells (ECs) that constitute the inner surface of blood vessels are
essential for new vessel formation and organ homeostasis. ECs display remarkable …

Age-related diseases, such as Parkinson's disease, Alzheimer's disease, cardiovascular
diseases, cancers, and age-related macular disease, have become increasingly prominent …

Endothelial cells (ECs) that line vascular and lymphatic vessels are being increasingly
recognized as important to organ function in health and disease. ECs participate not only in …

Liver sinusoidal endothelial cells (LSECs) are key players in maintaining hepatic
homeostasis. They also play crucial roles during liver injury by communicating with liver cell …