Pain induces stable, active microcircuits in the somatosensory cortex that provide a therapeutic target

T Okada, D Kato, Y Nomura, N Obata, X Quan… - Science …, 2021 - science.org
Sustained neuropathic pain from injury or inflammation remains a major burden for society.
Rodent pain models have informed some cellular mechanisms increasing neuronal …

Integrated World Modeling Theory (IWMT) implemented: towards reverse engineering consciousness with the free energy principle and active inference

A Safron - Active Inference: First International Workshop, IWAI …, 2020 - Springer
Abstract Integrated World Modeling Theory (IWMT) is a synthetic model that attempts to unify
theories of consciousness within the Free Energy Principle and Active Inference framework …

Intrinsic dynamics and neural implementation of a hypothalamic line attractor encoding an internal behavioral state

A Vinograd, A Nair, SW Linderman, DJ Anderson - bioRxiv, 2024 - biorxiv.org
Line attractors are emergent population dynamics hypothesized to encode continuous
variables such as head direction and internal states. In mammals, direct evidence of neural …

Potassium-selective channelrhodopsins

EG Govorunova, OA Sineshchekov… - Biophysics and …, 2023 - jstage.jst.go.jp
Since their discovery 21 years ago, channelrhodopsins have come of age and have become
indispensable tools for optogenetic control of excitable cells such as neurons and myocytes …