[HTML][HTML] iTReX: Interactive exploration of mono-and combination therapy dose response profiling data
High throughput screening methods, measuring the sensitivity and resistance of tumor cells
to drug treatments have been rapidly evolving. Not only do these screens allow correlating …
to drug treatments have been rapidly evolving. Not only do these screens allow correlating …
US EPA: Is there room to open a new window for evaluating potential sub-threshold effects and ecological risks?
With a rule published on 6 January 2021, the US Environmental Protection Agency (EPA)
considers for the first time sub-threshold responses, abandoning the use of default dose …
considers for the first time sub-threshold responses, abandoning the use of default dose …
Bayesian based similarity assessment of nanomaterials to inform grouping
Nanoforms can be manufactured in plenty of variants by differing their physicochemical
properties and toxicokinetic behaviour which can affect their hazard potential. To avoid …
properties and toxicokinetic behaviour which can affect their hazard potential. To avoid …
Evolutionary Computation in bioinformatics: A survey
Y Zhang, L Cheng, G Chen, D Alghazzawi - Neurocomputing, 2024 - Elsevier
Bioinformatics is a subject that studies life phenomena by using mathematical and
information science theories and techniques. Its main tasks, such as DNA sequence …
information science theories and techniques. Its main tasks, such as DNA sequence …
Optimizing the parameters of a physical exercise dose-response model: an algorithmic comparison
The purpose of this research was to compare the robustness and performance of a local and
global optimization algorithm applied to the problem of fitting the parameters of a non-linear …
global optimization algorithm applied to the problem of fitting the parameters of a non-linear …
Extending the lymphoblastoid cell line model for drug combination pharmacogenomics
Combination drug therapies have become an integral part of precision oncology, and while
evidence of clinical effectiveness continues to grow, the underlying mechanisms supporting …
evidence of clinical effectiveness continues to grow, the underlying mechanisms supporting …
The utility of mathematical fitness-fatigue models for assisting with the planning of physical training for sport: from in silico experiments employing synthetic data, lower …
BH Stephens Hemingway - 2021 - rgu-repository.worktribe.com
The greatest potential application of mathematical models in sport science is to predict future
performance of individual athletes in response to training, with sufficient accuracy to assist …
performance of individual athletes in response to training, with sufficient accuracy to assist …
[图书][B] Statistical Methods for Drug Synergy Analysis
J Ma - 2020 - search.proquest.com
The effectiveness of drug combinations for treatment of a variety of complex diseases is well
established." Drug cocktail" treatments are often prescribed to improve the overall efficacy …
established." Drug cocktail" treatments are often prescribed to improve the overall efficacy …