The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …

Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Highlights•Ideal mass spectrometer for MALDI MSI would satisfy the '4S-criteria for
performance'(speed, specificity, spatial resolution and sensitivity).•Quantification MALDI MSI …

Compared to conventional optical microscopy techniques, mass spectrometry imaging (MSI)
or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique which can …

Metabolomics is one omics approach that can be used to acquire comprehensive
information on the composition of a metabolite pool to provide a functional screen of the …

Spatial metabolomics describes the location and chemistry of small molecules involved in
metabolic phenotypes, defence molecules and chemical interactions in natural communities …

Secondary ion mass spectrometry (SIMS) has become an increasingly utilized tool in
biologically relevant studies. Of these, high lateral resolution methodologies using the …

Formalin-fixed and paraffin-embedded (FFPE) tissue specimens are the gold standard for
histological examination, and they provide valuable molecular information in tissue-based …

Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

Mass spectrometry imaging (MSI) has become an important analytical tool for the label‐free
chemical imaging of diverse molecules in biological specimens. This minireview surveys …