NKG2D is an activating receptor expressed by all NK cells and subsets of T cells. It serves
as a major recognition receptor for detection and elimination of transformed and infected …

The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly
diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal …

Natural killer group 2, member D (NKG2D) is an activating receptor present on the surface of
natural killer (NK) cells, some NKT cells, CD8+ cytotoxic T cells, γδ T cells, and under certain …

Human cytomegalovirus (HCMV) infection induces both innate immune responses including
Natural Killer cells as well as adaptive humoral and cell mediated (CD4+ helper, CD8+ …

NKG2D (natural-killer group 2, member D) is a powerful activating receptor expressed by
natural killer (NK) cells and T cells that regulates immune responses during infection, cancer …

Recent evidence indicates that natural killer (NK) cells can negatively regulate T-cell
responses, but the mechanisms behind this phenomenon as a consequence of NK–T-cell …

Given large sample sizes, whole genome screens are now able to identify even quite
modest contributions of common human genetic variation to disease. These approaches …

Major mechanisms for the recognition of pathogens by immune cells have evolved to
employ classical and non-classical major histocompatibility complex class I (MHC I) …

In mouse models of chronic inflammatory diseases, Natural Killer (NK) cells can play an
immunoregulatory role by eliminating chronically activated leukocytes. Indirect evidence …

Major histocompatibility complex (MHC) variation is a key determinant of susceptibility and
resistance to a large number of infectious, autoimmune and other diseases. Identification of …