[HTML][HTML] In vivo corneal elastography: A topical review of challenges and opportunities

G Lan, MD Twa, C Song, JP Feng, Y Huang… - Computational and …, 2023 - Elsevier
Clinical measurement of corneal biomechanics can aid in the early diagnosis, progression
tracking, and treatment evaluation of ocular diseases. Over the past two decades …

The development and clinical application of innovative optical ophthalmic imaging techniques

P Alexopoulos, C Madu, G Wollstein… - Frontiers in …, 2022 - frontiersin.org
The field of ophthalmic imaging has grown substantially over the last years. Massive
improvements in image processing and computer hardware have allowed the emergence of …

Wave-based optical coherence elastography: the 10-year perspective

F Zvietcovich, KV Larin - Progress in Biomedical Engineering, 2022 - iopscience.iop.org
After ten years of progress and innovation, optical coherence elastography (OCE) based on
the propagation of mechanical waves has become one of the major and the most studied …

In vivo stiffness measurement of epidermis, dermis, and hypodermis using broadband Rayleigh-wave optical coherence elastography

X Feng, GY Li, A Ramier, AM Eltony, SH Yun - Acta Biomaterialia, 2022 - Elsevier
Traveling-wave optical coherence elastography (OCE) is a promising technique to measure
the stiffness of biological tissues. While OCE has been applied to relatively homogeneous …

Motion-tracking Brillouin microscopy for in-vivo corneal biomechanics mapping

H Zhang, L Asroui, JB Randleman… - Biomedical Optics …, 2022 - opg.optica.org
Corneal biomechanics play a critical role in maintaining corneal shape and thereby directly
influence visual acuity. However, direct corneal biomechanical measurement in-vivo with …

Measuring mechanical anisotropy of the cornea with Brillouin microscopy

AM Eltony, P Shao, SH Yun - Nature communications, 2022 - nature.com
Load-bearing tissues are typically fortified by networks of protein fibers, often with
preferential orientations. This fiber structure imparts the tissues with direction-dependent …

Optical coherence elastography for assessing the influence of intraocular pressure on elastic wave dispersion in the cornea

MG Sun, T Son, J Crutison, V Guaiquil, S Lin… - Journal of the …, 2022 - Elsevier
The cornea is a highly specialized organ that relies on its mechanical stiffness to maintain its
aspheric geometry and refractive power, and corneal diseases such as keratoconus have …

Revealing regional variations in scleral shear modulus in a rabbit eye model using multi-directional ultrasound optical coherence elastography

L Villegas, F Zvietcovich, S Marcos, JS Birkenfeld - Scientific Reports, 2024 - nature.com
The mechanical properties of the sclera play a critical role in supporting the ocular structure
and maintaining its shape. However, non-invasive measurements to quantify scleral …

Simultaneous tensile and shear measurement of the human cornea in vivo using S0-and A0-wave optical coherence elastography

GY Li, X Feng, SH Yun - Acta Biomaterialia, 2024 - Elsevier
Understanding corneal stiffness is valuable for improving refractive surgery, detecting
corneal abnormalities, and assessing intraocular pressure. However, accurately measuring …

In Vivo Corneal Stiffness Mapping by the Stress-Strain Index Maps and Brillouin Microscopy

BT Lopes, A Elsheikh - Current eye research, 2023 - Taylor & Francis
The study of corneal stiffness in vivo has numerous clinical applications such as the
measurement of intraocular pressure, the preoperative screening for iatrogenic ectasia after …