Nanopore-based technologies beyond DNA sequencing
Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …
Engineering biological nanopore approaches toward protein sequencing
Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …
protein studies, while the methods we have for identifying and quantifying individual proteins …
A guide to signal processing algorithms for nanopore sensors
Nanopore technology holds great promise for a wide range of applications such as
biomedical sensing, chemical detection, desalination, and energy conversion. For sensing …
biomedical sensing, chemical detection, desalination, and energy conversion. For sensing …
Estimation of shape, volume, and dipole moment of individual proteins freely transiting a synthetic nanopore
This paper demonstrates that high-bandwidth current recordings in combination with low-
noise silicon nitride nanopores make it possible to determine the molecular volume …
noise silicon nitride nanopores make it possible to determine the molecular volume …
Solid-State Nanopore Distinguishes Ferritin and Apo-Ferritin with Identical Exteriors through Amplified Flexibility at Single-Molecule Level
YD Yin, FF Chen, J Hu, L Yang, XT Song… - Analytical …, 2023 - ACS Publications
Protein identification and discrimination at the single-molecule level are big challenges.
Solid-state nanopores as a sensitive biosensor have been used for protein analysis …
Solid-state nanopores as a sensitive biosensor have been used for protein analysis …
Allosteric Switching of Calmodulin in a Mycobacterium smegmatis porin A (MspA) Nanopore‐Trap
Recent developments concerning large protein nanopores suggest a new approach to
structure profiling of native folded proteins. In this work, the large vestibule of Mycobacterium …
structure profiling of native folded proteins. In this work, the large vestibule of Mycobacterium …
[HTML][HTML] Noise in nanopore sensors: Sources, models, reduction, and benchmarking
Label-free nanopore sensors have emerged as a new generation technology of DNA
sequencing and have been widely used for single molecule analysis. Since the first α …
sequencing and have been widely used for single molecule analysis. Since the first α …
Quantifying nanoparticle layer topography: Theoretical modeling and atomic force microscopy investigations
Z Adamczyk, M Sadowska, M Nattich-Rak - Langmuir, 2023 - ACS Publications
A comprehensive method consisting of theoretical modeling and experimental atomic force
microscopy (AFM) measurements was developed for the quantitative analysis of …
microscopy (AFM) measurements was developed for the quantitative analysis of …
The promise of nanopore technology: Advances in the discrimination of protein sequences and chemical modifications
Only a small percent of human genomic DNA encodes for proteins. Additionally, protein
isoforms variants and chemical modifications are not coded in the genome read by the cell …
isoforms variants and chemical modifications are not coded in the genome read by the cell …
High Accuracy Protein Identification: Fusion of Solid‐State Nanopore Sensing and Machine Learning
S Dutt, H Shao, B Karawdeniya… - Small …, 2023 - Wiley Online Library
Proteins are arguably one of the most important class of biomarkers for health diagnostic
purposes. Label‐free solid‐state nanopore sensing is a versatile technique for sensing and …
purposes. Label‐free solid‐state nanopore sensing is a versatile technique for sensing and …