Autonomic Nervous System Dysfunction: JACC Focus Seminar

JJ Goldberger, R Arora, U Buckley… - Journal of the American …, 2019 - jacc.org
Autonomic nervous system control of the heart is a dynamic process in both health and
disease. A multilevel neural network is responsible for control of chronotropy, lusitropy …

Role of the autonomic nervous system in modulating cardiac arrhythmias

MJ Shen, DP Zipes - Circulation research, 2014 - Am Heart Assoc
The autonomic nervous system plays an important role in the modulation of cardiac
electrophysiology and arrhythmogenesis. Decades of research has contributed to a better …

Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy

PS Chen, LS Chen, MC Fishbein, SF Lin… - Circulation …, 2014 - Am Heart Assoc
Autonomic nervous system activation can induce significant and heterogeneous changes of
atrial electrophysiology and induce atrial tachyarrhythmias, including atrial tachycardia and …

Pathophysiological mechanisms of atrial fibrillation: a translational appraisal

U Schotten, S Verheule, P Kirchhof… - Physiological …, 2011 - journals.physiology.org
Atrial fibrillation (AF) is an arrhythmia that can occur as the result of numerous different
pathophysiological processes in the atria. Some aspects of the morphological and …

Overview of basic mechanisms of cardiac arrhythmia

C Antzelevitch, A Burashnikov - Cardiac …, 2011 - cardiacep.theclinics.com
A cardiac arrhythmia simply defined is a variation from the normal heart rate and/or rhythm
that is not physiologically justified. Recent years have witnessed important advances in our …

[HTML][HTML] Circadian rhythm of cardiac electrophysiology, arrhythmogenesis, and the underlying mechanisms

N Black, A D'Souza, Y Wang, H Piggins, H Dobrzynski… - Heart rhythm, 2019 - Elsevier
Cardiac arrhythmias are a leading cause of cardiovascular death. It has long been accepted
that life-threatening cardiac arrhythmias (ventricular tachycardia, ventricular fibrillation, and …

Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop

EJ Benjamin, PS Chen, DE Bild, AM Mascette… - Circulation, 2009 - Am Heart Assoc
The National Heart, Lung, and Blood Institute convened an expert panel April 28 to 29,
2008, to identify gaps and recommend research strategies to prevent atrial fibrillation (AF) …

Role of autonomic nervous system in atrial fibrillation

D Linz, AD Elliott, M Hohl, V Malik, U Schotten… - International Journal of …, 2019 - Elsevier
Atrial fibrillation is the most common sustained arrhythmia and is associated with significant
morbidity and mortality. The autonomic nervous system has a significant role in the milieu …

Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines

AY Tan, S Zhou, M Ogawa, J Song, M Chu, H Li… - Circulation, 2008 - Am Heart Assoc
Background—The relationship between autonomic activation and the mechanisms of
paroxysmal atrial fibrillation remains unclear. Methods and Results—We implanted a …

Dynamics of atrial fibrillation mechanisms and comorbidities

J Heijman, D Linz, U Schotten - Annual review of physiology, 2021 - annualreviews.org
Atrial fibrillation (AF) contributes to morbidity and mortality of millions of individuals. Its
molecular, cellular, neurohumoral, and hemodynamic pathophysiological mechanisms are …