This narrative review aims to discuss the more relevant evidence on the role of linoleic acid
(LA), a n-6 essential fatty acid that constitutes the predominant proportion of dietary …

Docosahexaenoic acid (DHA) is a structural constituent of membranes specifically in the
central nervous system. Its accumulation in the fetal brain takes place mainly during the last …

Ferroptosis is an iron-dependent regulated necrosis mediated by lipid peroxidation. Cancer
cells survive under metabolic stress conditions by altering lipid metabolism, which may alter …

Alpha-linolenic acid (ALA) is an essential fatty acid and the substrate for the synthesis of
longer-chain, more unsaturated ω-3 fatty acids, eicosapentaenoic acid (EPA) …

Many clinical and animal studies demonstrate the importance of long-chain polyunsaturated
fatty acids (LCPUFA) in neural development and neurodegeneration. This review will focus …

Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …

Docosahexaenoic acid (DHA) is a long-chain, highly unsaturated omega-3 (n-3) fatty acid. It
has a structure that gives it unique physical and functional properties. DHA is metabolically …

Maternal nutrition has little or no effect on many nutrients in human milk; for others, human
milk may not be designed as a primary nutritional source for the infant; and for a few …

Several sources of information suggest that human beings evolved on a diet that had a ratio
of omega-6 to omega-3 fatty acids (FA) of about 1/1; whereas today, Western diets have a …

Blood low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol
and triglyceride levels are risk factors for cardiovascular disease. To dissect the polygenic …