Urocortins, three paralogs of the stress-related peptide corticotropin-releasing factor (CRF)
found in bony fish, amphibians, birds, and mammals, have unique phylogenies …

Apoptosis, a genetically programmed form of cell death, contributes to myocyte cell loss in a
variety of cardiac pathologies, including cardiac failure and those related to …

In addition to their normal physiological role in ATP production and metabolism,
mitochondria exhibit a dark side mediated by the opening of a non-specific pore in the inner …

Aims Protein kinase C epsilon (PKCε) is critical for cardiac protection from ischaemia and
reperfusion (IR) injury. PKCε substrates that mediate cytoprotection reside in the …

Aim: To investigate the protective effect of tribulosin, a monomer of the gross saponins from
Tribulus terrestris, against cardiac ischemia/reperfusion injury and the underlying …

Mitochondria mediate diverse cellular functions including energy generation and ROS
(reactive oxygen species) production and contribute to signal transduction. Mitochondria are …

Reactive oxygen species (ROS) and endoplasmic reticulum (ER) stress are paradoxically
implicated in myocardial ischemia/reperfusion (I/R) injury and cardioprotection. However …

Urocortin (UCN) protects hearts against ischemia and reperfusion injury whether given
before ischemia or at reperfusion. Here we investigate the roles of PKC, reactive oxygen …

The effects of titanium dioxide (TiO2) nanoparticles (NPs) on the differentiation of neural
stem cells are reported. Our findings indicate that TiO2 NPs lead to a differentiational …

Insulin resistance (IR) in skeletal muscle is an important component of both type 2 diabetes
and the syndrome of sarcopaenic obesity, for which there are no effective therapies …