[HTML][HTML] Roles of STAT3 in the pathogenesis and treatment of glioblastoma
W Fu, X Hou, L Dong, W Hou - Frontiers in cell and developmental …, 2023 - frontiersin.org
Glioblastoma (GBM) is the most malignant of astrocytomas mainly involving the cerebral
hemispheres and the cerebral cortex. It is one of the fatal and refractory solid tumors, with a …
hemispheres and the cerebral cortex. It is one of the fatal and refractory solid tumors, with a …
STAT3 in medulloblastoma: a key transcriptional regulator and potential therapeutic target
A Zaiter, ZF Audi, F Shawraba, Z Saker… - Molecular Biology …, 2022 - Springer
Medulloblastoma is the most common malignant brain tumor of childhood accounting for
about 60% of all pediatric embryonal tumors. Despite improvements in the overall survival …
about 60% of all pediatric embryonal tumors. Despite improvements in the overall survival …
[HTML][HTML] Tumor-associated macrophages correlate with prognosis in medulloblastoma
J Zhang, X Yuan, Y Wang, J Liu, Z Li, S Li, Y Liu… - Frontiers in …, 2022 - frontiersin.org
Purpose Macrophage polarization plays an essential role in the tumor microenvironment of
brain tumors. However, the role of tumor-associated macrophages (TAMs) in …
brain tumors. However, the role of tumor-associated macrophages (TAMs) in …
[HTML][HTML] LLL12B, a novel small-molecule STAT3 inhibitor, induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer cells
Persistent STAT3 signaling plays a pivotal role in human tumor malignancy, including triple-
negative breast cancer (TNBC). There are few treatment options currently available for …
negative breast cancer (TNBC). There are few treatment options currently available for …
The pivotal role of irradiation‐induced apoptosis in the pathogenesis and therapy of medulloblastoma
SA Richard - Cancer Reports, 2024 - Wiley Online Library
Background Medulloblastoma (MB) is a rare primitive neuroectodermal tumors originating
from the cerebellum. MB is the most common malignant primary brain tumor of childhood …
from the cerebellum. MB is the most common malignant primary brain tumor of childhood …