Scleral structure and biomechanics

C Boote, IA Sigal, R Grytz, Y Hua, TD Nguyen… - Progress in retinal and …, 2020 - Elsevier
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …

Measurement of tissue optical properties in the context of tissue optical clearing

AN Bashkatov, KV Berezin… - … of biomedical optics, 2018 - spiedigitallibrary.org
Nowadays, dynamically developing optical (photonic) technologies play an ever-increasing
role in medicine. Their adequate and effective implementation in diagnostics, surgery, and …

[HTML][HTML] Age-and race-related differences in human scleral material properties

R Grytz, MA Fazio, V Libertiaux, L Bruno… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: We tested the hypothesis that there are age-and race-related differences in
posterior scleral material properties, using eyes from human donors of European (20–90 …

Collagen structure and mechanical properties of the human sclera: analysis for the effects of age

B Coudrillier, J Pijanka, J Jefferys… - Journal of …, 2015 - asmedigitalcollection.asme.org
The objective of this study was to measure the collagen fiber structure and estimate the
material properties of 7 human donor scleras, from age 53 to 91. The specimens were …

[HTML][HTML] Quantitative mapping of collagen fiber orientation in non-glaucoma and glaucoma posterior human sclerae

JK Pijanka, B Coudrillier, K Ziegler… - … & visual science, 2012 - tvst.arvojournals.org
Purpose.: The posterior sclera has a major biomechanical influence on the optic nerve head,
and may therefore be important in glaucoma. Scleral material properties are influenced …

Material properties of the posterior human sclera

R Grytz, MA Fazio, MJA Girard, V Libertiaux… - Journal of the …, 2014 - Elsevier
To characterize the material properties of posterior and peripapillary sclera from human
donors, and to investigate the macro-and micro-scale strains as potential control …

Biomechanics of the posterior eye: a critical role in health and disease

IC Campbell, B Coudrillier… - Journal of …, 2014 - asmedigitalcollection.asme.org
The posterior eye is a complex biomechanical structure. Delicate neural and vascular
tissues of the retina, choroid, and optic nerve head that are critical for visual function are …

Polarization microscopy for characterizing fiber orientation of ocular tissues

NJ Jan, JL Grimm, H Tran, KL Lathrop… - Biomedical optics …, 2015 - opg.optica.org
Characterizing the collagen fiber orientation and organization in the eye is necessary for a
complete understanding of ocular biomechanics. In this study, we assess the performance of …

[HTML][HTML] Collagen architecture of the posterior pole: high-resolution wide field of view visualization and analysis using polarized light microscopy

NJ Jan, K Lathrop, IA Sigal - Investigative ophthalmology & …, 2017 - iovs.arvojournals.org
Purpose: The purpose of this study was to leverage polarized light microscopy (PLM) to
visualize the collagen fiber architecture of posterior pole and optic nerve head with …

Translating ocular biomechanics into clinical practice: current state and future prospects

MJA Girard, WJ Dupps, M Baskaran… - Current eye …, 2015 - Taylor & Francis
Biomechanics is the study of the relationship between forces and function in living
organisms and is thought to play a critical role in a significant number of ophthalmic …