Concerns for anaphylaxis may hamper severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) immunization efforts. We convened a multidisciplinary group of international …

A massive COVID-19 vaccination campaign is underway worldwide. Epidemiological data
from studies indicate excellent efficacy and safety profile for COVID-19 vaccines. However …

Abstract BNT162b2, a nucleoside-modified mRNA formulated in lipid nanoparticles that
encodes the SARS-CoV-2 spike glycoprotein (S) stabilized in its prefusion conformation, has …

Background Despite the high efficacy of the BNT162b2 messenger RNA vaccine against
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), rare breakthrough …

The effectiveness of the coronavirus disease 2019 (COVID-19) BNT162b2 vaccine in
preventing disease and reducing viral loads of breakthrough infections (BTIs) has been …

The BNT162b2 mRNA vaccine is highly effective against SARS-CoV-2. However,
apprehension exists that variants of concern (VOCs) may evade vaccine protection, due to …

The effectiveness of vaccines against COVID-19 on the individual level is well established.
However, few studies have examined vaccine effectiveness against transmission. We used …

The global drive to vaccinate against severe acute respiratory syndrome-coronavirus-2
(SARS-CoV-2) began in December 2020 with countries in Europe, Middle East, and North …

Patients with type 2 diabetes (T2D) are characterized by blunted immune responses, which
are affected by glycaemic control. Whether glycaemic control influences the response to …

Synthetic mRNA provides a template for the synthesis of any given protein, protein fragment
or peptide and lends itself to a broad range of pharmaceutical applications, including …