Abstract The concept of 1, 3‐dipolar cycloadditions was presented by Rolf Huisgen 60 years
ago. Previously unknown reactive intermediates, for example azomethine ylides, were …

The isoxazolidine ring represents one of the privileged structures in medicinal chemistry,
and there have been an increasing number of studies on isoxazolidine and isoxazolidine …

Chiral phosphoric acids derived from axially chiral biaryls and related chiral Brønsted acids
have emerged as an attractive and widely applicable class of enantioselective …

Azomethine imines are considered 1, 3-dipoles of the aza-allyl type which are transient
intermediates and should be generated in situ but can also be stable and isolable …

The privileged spiro [pyrrolidin-3, 3′-oxindole] derivatives exhibit important biological
activities. An enantioselective organocatalytic approach to the rapid synthesis of spiro …

Although metal-free cycloadditions of cyclooctynes and azides to give stable 1, 2, 3-triazoles
have found wide utility in chemical biology and material sciences, there is an urgent need for …

The first catalytic enantioselective construction of a 3, 3′-pyrrolidinyldispirooxindole
scaffold has been established via organocatalytic asymmetric 1, 3-dipolar cycloadditions of …

Iodobenzene diacetate in MeOH containing a catalytic amount of TFA efficiently oxidizes
aldoximes to nitrile oxides. The latter may be trapped in situ with olefins in a bimolecular or …

A Brønsted acid catalyzed three-component asymmetric 1, 3-dipolar addition reaction
between aldehydes, amino esters, and dipolarophiles by a new bisphosphoric acid, derived …

Hypervalent iodine catalyzed oxidation of aldoximes using oxone as a terminal oxidant
generates nitrile oxides, which react with alkenes and alkynes to give the corresponding …