Progressive multifocal leukoencephalopathy and the spectrum of JC virus-related disease
Progressive multifocal leukoencephalopathy (PML) is a devastating CNS infection caused
by JC virus (JCV), a polyomavirus that commonly establishes persistent, asymptomatic …
by JC virus (JCV), a polyomavirus that commonly establishes persistent, asymptomatic …
Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain
MW Ferenczy, LJ Marshall, CDS Nelson… - Clinical microbiology …, 2012 - Am Soc Microbiol
Progressive multifocal leukoencephalopathy (PML) is a debilitating and frequently fatal
central nervous system (CNS) demyelinating disease caused by JC virus (JCV), for which …
central nervous system (CNS) demyelinating disease caused by JC virus (JCV), for which …
Management of the immune reconstitution inflammatory syndrome
G Meintjes, J Scriven, S Marais - Current HIV/AIDS Reports, 2012 - Springer
The immune reconstitution inflammatory syndrome (IRIS) is a frequent early complication of
antiretroviral therapy (ART) in patients with advanced HIV. Because there is no confirmatory …
antiretroviral therapy (ART) in patients with advanced HIV. Because there is no confirmatory …
Progressive multifocal leukoencephalopathy
R Weissert - Journal of neuroimmunology, 2011 - Elsevier
Progressive multifocal leukoencephalopathy (PML) is a disease of the central nervous
system (CNS) with destructive infection of oligodendrocytes by JC virus. PML belongs to the …
system (CNS) with destructive infection of oligodendrocytes by JC virus. PML belongs to the …
New insights on human polyomavirus JC and pathogenesis of progressive multifocal leukoencephalopathy
A Bellizzi, E Anzivino, DM Rodio… - Journal of …, 2013 - Wiley Online Library
John Cunningham virus (JCV) is a member of the Polyomaviridae family. It was first isolated
from the brain of a patient with Hodgkin disease in 1971, and since then the etiological …
from the brain of a patient with Hodgkin disease in 1971, and since then the etiological …
[PDF][PDF] John Cunningham virus: an overview on biology and disease of the etiological agent of the progressive multifocal leukoencephalopathy
V Pietropaolo, C Prezioso, F Bagnato… - New …, 2018 - newmicrobiologica.org
JCV is a small (∼ 45 nm), non-enveloped, circular, double-stranded DNA genome,
arranged in 72 viral capsomeres with icosahedral symmetry (Tan et al., 2009a). The genome …
arranged in 72 viral capsomeres with icosahedral symmetry (Tan et al., 2009a). The genome …
[HTML][HTML] Diagnosis and treatment of progressive multifocal leukoencephalopathy associated with multiple sclerosis therapies
EML Williamson, JR Berger - Neurotherapeutics, 2017 - Elsevier
Progressive multifocal leukoencephalopathy (PML) is a rare, but serious, complication
encountered in patients treated with a select number of disease-modifying therapies (DMTs) …
encountered in patients treated with a select number of disease-modifying therapies (DMTs) …
Sp1 sites in the noncoding control region of BK polyomavirus are key regulators of bidirectional viral early and late gene expression
T Bethge, HA Hachemi, J Manzetti, R Gosert… - Journal of …, 2015 - Am Soc Microbiol
In kidney transplant patients with BK polyomavirus (BKPyV) nephropathy, viral variants arise
bearing rearranged noncoding control regions (rr-NCCRs) that increase viral early gene …
bearing rearranged noncoding control regions (rr-NCCRs) that increase viral early gene …
Progressive multifocal leukoencephalopathy: clinical and molecular aspects
E Tavazzi, MK White, K Khalili - Reviews in Medical Virology, 2012 - Wiley Online Library
The fatal CNS demyelinating disease, progressive multifocal leukoencephalopathy (PML), is
rare and appears to occur almost always as a consequence of immune dysfunction. Thus, it …
rare and appears to occur almost always as a consequence of immune dysfunction. Thus, it …
Rearrangement in the hypervariable region of JC polyomavirus genomes isolated from patient samples and impact on transcription factor-binding sites and disease …
MP Wilczek, AMC Pike, SE Craig, MS Maginnis… - International Journal of …, 2022 - mdpi.com
JC polyomavirus (JCPyV) is the causative agent of the fatal, incurable, neurological disease,
progressive multifocal leukoencephalopathy (PML). The virus is present in most of the adult …
progressive multifocal leukoencephalopathy (PML). The virus is present in most of the adult …