A comprehensive review of risk factors for venous thromboembolism: from epidemiology to pathophysiology
Venous thromboembolism (VTE) is the third most common cause of death worldwide. The
incidence of VTE varies according to different countries, ranging from 1–2 per 1000 person …
incidence of VTE varies according to different countries, ranging from 1–2 per 1000 person …
Diagnosis, development, and treatment of portal vein thrombosis in patients with and without cirrhosis
NM Intagliata, SH Caldwell, A Tripodi - Gastroenterology, 2019 - Elsevier
Portal vein thrombosis unrelated to solid malignancy is common in patients with cirrhosis,
but less frequently observed in patients without cirrhosis. Prompt diagnosis and …
but less frequently observed in patients without cirrhosis. Prompt diagnosis and …
Thrombin generation assay and its application in the clinical laboratory
A Tripodi - Clinical chemistry, 2016 - academic.oup.com
BACKGROUND A gap exists between in vivo and ex vivo coagulation when investigated by
use of the coagulation tests prothrombin time (PT) and activated partial thromboplastin time …
use of the coagulation tests prothrombin time (PT) and activated partial thromboplastin time …
Hyperosmolar hyperglycemic state: a historic review of the clinical presentation, diagnosis, and treatment
FJ Pasquel, GE Umpierrez - Diabetes care, 2014 - Am Diabetes Assoc
The hyperosmolar hyperglycemic state (HHS) is the most serious acute hyperglycemic
emergency in patients with type 2 diabetes. von Frerichs and Dreschfeld described the first …
emergency in patients with type 2 diabetes. von Frerichs and Dreschfeld described the first …
Inflammation, obesity, and thrombosis
F Samad, W Ruf - Blood, The Journal of the American Society …, 2013 - ashpublications.org
Clinical and epidemiological studies support a connection between obesity and thrombosis,
involving elevated expression of the prothrombotic molecules plasminogen activator …
involving elevated expression of the prothrombotic molecules plasminogen activator …
Procoagulant activity in hemostasis and thrombosis: Virchow's triad revisited
Virchow's triad is traditionally invoked to explain pathophysiologic mechanisms leading to
thrombosis, alleging concerted roles for abnormalities in blood composition, vessel wall …
thrombosis, alleging concerted roles for abnormalities in blood composition, vessel wall …
Procoagulant imbalance in patients with non-alcoholic fatty liver disease
A Tripodi, AL Fracanzani, M Primignani… - Journal of …, 2014 - Elsevier
Background & Aims Non-alcoholic fatty liver disease (NAFLD) is characterized by increased
risk of cardiovascular events and liver-fibrosis. Both could be explained by a procoagulant …
risk of cardiovascular events and liver-fibrosis. Both could be explained by a procoagulant …
Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk
An enhanced thrombotic environment and premature atherosclerosis are key factors for the
increased cardiovascular risk in diabetes. The occlusive vascular thrombus, formed …
increased cardiovascular risk in diabetes. The occlusive vascular thrombus, formed …
Platelet activity and hypercoagulation in type 2 diabetes
L Pretorius, GJA Thomson, RCM Adams… - Cardiovascular …, 2018 - Springer
Background A strong correlation exists between type 2 diabetes mellitus (T2DM) and
cardiovascular disease (CVD), with CVD and the presence of atherosclerosis being the …
cardiovascular disease (CVD), with CVD and the presence of atherosclerosis being the …
[HTML][HTML] Differential contributions of monocyte‐and platelet‐derived microparticles towards thrombin generation and fibrin formation and stability
Summary Background: Microparticles (MPs) are sub‐micron vesicles shed by activated or
apoptotic cells, including platelets and monocytes. Increased circulating MPs are associated …
apoptotic cells, including platelets and monocytes. Increased circulating MPs are associated …