We present a testable hypothesis related to an origin of life on land in which fluctuating
volcanic hot spring pools play a central role. The hypothesis is based on experimental …

Prebiotic chemistry aims to explain how the biochemistry of life as we know it came to be.
Most efforts in this area have focused on provisioning compounds of importance to life by …

The RNA world concept is one of the most fundamental pillars of the origin of life theory,–. It
predicts that life evolved from increasingly complex self-replicating RNA molecules,,. The …

The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …

Although the mode of action of the ribosomes, the multi-component universal effective
protein-synthesis organelles, has been thoroughly explored, their mere appearance …

Progress in development of biophysical analytic approaches has recently crossed paths with
macromolecule condensates in cells. These cell condensates, typically termed liquid-like …

The ribosome is an ancient molecular fossil that provides a telescope to the origins of life.
Made from RNA and protein, the ribosome translates mRNA to coded protein in all living …

Iron oxyhydroxide minerals, known to be chemically reactive and significant for elemental
cycling, are thought to have been abundant in early-Earth seawater, sediments, and …

It is widely assumed that the condensation of building blocks into oligomers and polymers
was important in the origins of life. High activation energies, unfavorable thermodynamics …

Recent developments in Origins of Life research have focused on substantiating the
narrative of an abiotic emergence of nucleic acids from organic molecules of low molecular …