Human microbiome and prostate cancer development: current insights into the prevention and treatment

S Ohadian Moghadam, SA Momeni - Frontiers of Medicine, 2021 - Springer
The huge communities of microorganisms that symbiotically colonize humans are
recognized as significant players in health and disease. The human microbiome may …

The influence of statin medications on prostate-specific antigen levels

RJ Hamilton, KC Goldberg, EA Platz… - JNCI: Journal of the …, 2008 - academic.oup.com
Background Recent data suggest that statin use may be associated with a reduced risk of
advanced prostate cancer. However, the influence of statins on prostate-specific antigen …

Definition of outcome-based prostate-specific antigen (PSA) thresholds for advanced prostate cancer risk prediction

S Ferraro, M Bussetti, N Bassani, RS Rossi… - Cancers, 2021 - mdpi.com
Simple Summary In this study, we used a well calibrated risk prediction model to define
prostate-specific antigen (PSA) thresholds for identifying or excluding advanced prostate …

Exclusion of inflammation in the differential diagnosis of an elevated prostate-specific antigen (PSA)

S Loeb, SN Gashti, WJ Catalona - Urologic Oncology: Seminars and …, 2009 - Elsevier
Prostate inflammation can lead to an elevation in the serum PSA concentration and
confound the use of PSA kinetics. This can have considerable clinical consequences, since …

Canine-inspired chemometric analysis of volatile organic compounds in urine headspace to distinguish prostate cancer in mice and men

M Woollam, AP Siegel, A Munshi, S Liu, S Tholpady… - Cancers, 2023 - mdpi.com
Simple Summary Volatile organic compounds (VOCs) in urine headspace have been
previously shown to be potential biomarkers for prostate cancer. The aim of the current study …

Baseline prostate inflammation is associated with a reduced risk of prostate cancer in men undergoing repeat prostate biopsy: results from the REDUCE study

DM Moreira, JC Nickel, L Gerber, RL Muller… - Cancer, 2014 - Wiley Online Library
BACKGROUND The current study was performed to evaluate whether baseline acute and
chronic prostate inflammation among men with an initial negative biopsy for prostate cancer …

[HTML][HTML] Effects of Serenoa Repens, Selenium and Lycopene (Profluss®) on chronic inflammation associated with Benign Prostatic Hyperplasia: results of “FLOG” …

G Morgia, S Cimino, V Favilla, GI Russo… - International braz j …, 2013 - SciELO Brasil
Objective To evaluate the efficacy of Profluss® on prostatic chronic inflammation (PCI).
Materials and Methods We prospectively enrolled 168 subjects affected by LUTS due to …

[HTML][HTML] Progression of benign prostatic hyperplasia is associated with pro-inflammatory mediators and chronic activation of prostate-infiltrating lymphocytes

MM Norström, E Rådestad, B Sundberg, J Mattsson… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Benign prostatic hyperplasia (BPH) is a common chronic non-malignant condition whose
prevalence substantially increases with age. Immune cell infiltration and pro-inflammatory …

Intraprostatic inflammation is positively associated with serum PSA in men with PSA< 4 ng ml− 1, normal DRE and negative for prostate cancer

MH Umbehr, B Gurel, TJ Murtola, S Sutcliffe… - Prostate cancer and …, 2015 - nature.com
Background: Biopsies performed for elevated serum PSA often show inflammatory infiltrates.
However, the influence of intraprostatic inflammation on serum PSA in men without biopsy …

Association between periodontal disease and prostate‐specific antigen levels in chronic prostatitis patients

N Joshi, NF Bissada, D Bodner… - Journal of …, 2010 - Wiley Online Library
Background: Prostate‐specific antigen (PSA) is an inflammatory marker produced by the
epithelial cells of the prostate acini. In the presence of inflammation or malignancy of the …