Epstein Barr virus: development of vaccines and immune cell therapy for EBV-associated diseases

X Cui, CM Snapper - Frontiers in Immunology, 2021 - frontiersin.org
Epstein-Barr virus (EBV) is the first human tumor virus discovered and is strongly implicated
in the etiology of multiple lymphoid and epithelial cancers. Each year EBV associated …

Microbial dysbiosis in the gut drives systemic autoimmune diseases

WK Mousa, F Chehadeh, S Husband - Frontiers in immunology, 2022 - frontiersin.org
Trillions of microbes survive and thrive inside the human body. These tiny creatures are
crucial to the development and maturation of our immune system and to maintain gut …

Long-term outcomes of pediatric infections: from traditional infectious diseases to long Covid

D Buonsenso, LD Gennaro, CD Rose… - Future …, 2022 - Taylor & Francis
There is limited evidence available on the long-term impact of SARS-CoV-2 infection in
children. In this article, the authors analyze the recent evidence on pediatric long Covid and …

mRNA vaccines for COVID-19 and diverse diseases

A Hussain, H Yang, M Zhang, Q Liu, G Alotaibi… - Journal of Controlled …, 2022 - Elsevier
Since its outbreak in late 2019, the novel coronavirus disease 2019 (COVID-19) has spread
to every continent on the planet. The global pandemic has affected human health and …

Stress-induced Epstein-Barr virus reactivation

DG Sausen, MS Bhutta, ES Gallo, H Dahari… - Biomolecules, 2021 - mdpi.com
Epstein-Barr virus (EBV) is typically found in a latent, asymptomatic state in
immunocompetent individuals. Perturbations of the host immune system can stimulate viral …

Infectious Mononucleosis: diagnosis and clinical interpretation

P Naughton, M Healy, F Enright… - British journal of …, 2021 - Taylor & Francis
ABSTRACT EBV is the sole causative agent of the acute illness in humans described either
as infectious mononucleosis (IM), or glandular fever. IM, when not clinically silent, can …

Preparing previously COVID-19-positive patients for elective surgery: a framework for preoperative evaluation

N Bui, M Coetzer, KJ Schenning, AY O'Glasser - Perioperative Medicine, 2021 - Springer
The preoperative evaluation and risk assessment has always been a critical aspect of safe
surgical practice, and in the midst of the SARS-CoV-2 pandemic, it has become even more …

Suppression of cGAS-and RIG-I-mediated innate immune signaling by Epstein-Barr virus deubiquitinase BPLF1

WY Lui, A Bharti, NHM Wong, S Jangra… - PLoS …, 2023 - journals.plos.org
Epstein-Barr virus (EBV) has developed effective strategies to evade host innate immune
responses. Here we reported on mitigation of type I interferon (IFN) production by EBV …

The development of mRNA vaccines for infectious diseases: recent updates

Nitika, J Wei, AM Hui - Infection and drug resistance, 2021 - Taylor & Francis
Abstract mRNA-based technologies have been of interest for the past few years to be used
for therapeutics. Several mRNA vaccines for various diseases have been in preclinical and …

mRNA-based modalities for infectious disease management

M Zhang, A Hussain, H Yang, J Zhang, XJ Liang… - Nano research, 2023 - Springer
The novel coronavirus disease 2019 (COVID-19) is still rampant all over the world, causing
incalculable losses to the world. Major pharmaceutical organizations around the globe are …