Hypothermia therapy is an old and important method of neuroprotection. Until now, many
neurological diseases such as stroke, traumatic brain injury, intracranial pressure elevation …

Intermittent fasting (IF) is a dietary protocol where energy restriction is induced by alternate
periods of ad libitum feeding and fasting. Prophylactic intermittent fasting has been shown to …

The complement system is a component of the immune system involved in both recognition
and response to pathogens, and it is implicated in an increasing number of homeostatic and …

The recognition that complement proteins are abundantly present and can have
pathological roles in neurological conditions offers broad scope for therapeutic intervention …

Inter-α inhibitor proteins (IAIPs) are a family of endogenous plasma and extracellular matrix
molecules. IAIPs suppress proinflammatory cytokines, limit excess complement activation …

Glial cells are non-neuronal components of the central nervous system (CNS). They are
endowed with diverse functions and are provided with tools to detect their own activities and …

Ephrin (Eph) signaling within the central nervous system is known to modulate axon
guidance, synaptic plasticity, and to promote long-term potentiation. We investigated the …

In the search for a therapeutic schedule for spinal cord injury, it is necessary to understand
key genes and their corresponding regulatory networks involved in the spinal cord injury …

Background Ischemic stroke (IS) is one of most common causes of disability in adults
worldwide. However, there is still a lack of effective and reliable diagnostic markers and …

Hypothermia is a promising neuroprotective therapy that has been shown to reduce
apoptosis after an ischemic insult. This study evaluated the effect of mild hypothermia on …