Diabetes mellitus predisposes affected individuals to a significant spectrum of
cardiovascular complications, one of the most debilitating in terms of prognosis is heart …

Heart failure is a complex clinical syndrome, the incidence and prevalence of which is
increased in diabetes mellitus, pre-diabetes, and obesity. Although this may arise from …

Exercise training has been widely recognized as a healthy lifestyle as well as an effective
non-drug therapeutic strategy for cardiovascular diseases (CVD). Functional and …

The benefits of exercise on the heart are well recognized, and clinical studies have
demonstrated that exercise is an intervention that can improve cardiac function in heart …

Aims The glucose-driven enzymatic modification of myocardial proteins by the sugar moiety,
β-N-acetylglucosamine (O-GlcNAc), is increased in pre-clinical models of diabetes …

Diabetes is associated with an increased risk of heart failure (HF). This is commonly termed
diabetic cardiomyopathy and is often characterised by increased cardiac fibrosis …

Diabetic cardiomyopathy is a distinct pathology independent of co-morbidities such as
coronary artery disease and hypertension. Diminished glucose uptake due to impaired …

Heart failure represents the end point of a variety of cardiovascular diseases. It is a growing
health burden and a leading cause of death worldwide. To date, limited treatment options …

Exercise has well-recognized beneficial effects on the whole body. Previous studies suggest
that exercise could promote tissue regeneration and repair in various organs. In this review …

Diabetic dysbiosis has been described as a novel key player in diabetes and diabetic
complications. However, the cellular/molecular alterations associated with dysbiosis remain …