The complex aetiology of cerebral palsy

SJ Korzeniewski, J Slaughter, M Lenski… - Nature Reviews …, 2018 - nature.com
Cerebral palsy (CP) is the most prevalent, severe and costly motor disability of childhood.
Consequently, CP is a public health priority for prevention, but its aetiology has proved …

[HTML][HTML] Cerebral palsy: causes, pathways, and the role of genetic variants

AH MacLennan, SC Thompson, J Gecz - American journal of obstetrics and …, 2015 - Elsevier
Cerebral palsy (CP) is heterogeneous with different clinical types, comorbidities, brain
imaging patterns, causes, and now also heterogeneous underlying genetic variants. Few …

Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes

R Romero, J Miranda, P Chaemsaithong… - The journal of …, 2015 - Taylor & Francis
Objective: The objectives of this study were to:(1) determine the amniotic fluid (AF)
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …

The global impact of pre-eclampsia and eclampsia

L Duley - Seminars in perinatology, 2009 - Elsevier
Over half a million women die each year from pregnancy related causes, 99% in low and
middle income countries. In many low income countries, complications of pregnancy and …

Directed acyclic graphs: a tool for causal studies in paediatrics

TC Williams, CC Bach, NB Matthiesen… - Pediatric …, 2018 - nature.com
Many paediatric clinical research studies, whether observational or interventional, have as
an eventual aim the identification or quantification of causal relationships. One might ask …

The epidemiology of cerebral palsy: incidence, impairments and risk factors

E Odding, ME Roebroeck, HJ Stam - Disability and rehabilitation, 2006 - Taylor & Francis
Purpose. Describing the epidemiology of cerebral palsy (CP), its impairments and risk
factors. Method. Literature review 1965–2004. Search terms: Cerebral palsy, incidence …

Effects of prenatal infection on brain development and behavior: a review of findings from animal models

P Boksa - Brain, behavior, and immunity, 2010 - Elsevier
Epidemiological studies with human populations indicate associations between maternal
infection during pregnancy and increased risk in offspring for central nervous system (CNS) …

The fetal inflammatory response syndrome

R Gomez, R Romero, F Ghezzi, BH Yoon… - American journal of …, 1998 - Elsevier
OBJECTIVE: The objective of this study was to determine the frequency and clinical
significance of a systemic inflammatory response as defined by an elevated plasma …

Antibiotics for preterm rupture of membranes

S Kenyon, M Boulvain, JP Neilson… - Cochrane database …, 1996 - cochranelibrary.com
Background Premature birth carries substantial neonatal morbidity and mortality. Subclinical
infection is associated with preterm rupture of membranes (PROM). Prophylactic maternal …

Strength of association between umbilical cord pH and perinatal and long term outcomes: systematic review and meta-analysis

GL Malin, RK Morris, KS Khan - Bmj, 2010 - bmj.com
Objective To evaluate the association between umbilical cord pH at birth and long term
outcomes. Design Systematic review and meta-analysis. Data sources Medline (1966 …