Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Aspergillus fumigatus is the main causal agent of invasive aspergillosis (IA), however other
species of the genus can also cause IA, such as Aspergillus flavus, Aspergillus terreus …

The frequency of antifungal resistance, particularly to the azole class of ergosterol
biosynthetic inhibitors, is a growing global health problem. Survival rates for those infected …

The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

Fungal-mediated disease progression and antifungal drug efficacy are significantly
impacted by the dynamic infection microenvironment. At the site of infection, oxygen often …

Fungal pathogens are a severe public health problem. The leading causative agents of
systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus …

The superfamily of ATP-binding cassette (ABC) transporters is a large family of proteins with
a wide substrate repertoire and range of functions. The main role of these proteins is in the …

Antifungal resistance is a growing concern as it poses a significant threat to public health.
Fungal infections are a significant cause of morbidity and mortality, especially in …

We investigated the prevalence of azole resistance of Aspergillus fumigatus isolates in the
Netherlands by screening clinical A. fumigatus isolates for azole resistance during 2013 …

Budding yeast Saccharomyces cerevisiae survives in microenvironments utilizing networks
of regulators and ATP‐binding cassette (ABC) transporters to circumvent toxins and a variety …