Phytosomes as innovative delivery systems for phytochemicals: A comprehensive review of literature

M Barani, E Sangiovanni, M Angarano… - International Journal …, 2021 - Taylor & Francis
Nowadays, medicinal herbs and their phytochemicals have emerged as a great therapeutic
option for many disorders. However, poor bioavailability and selectivity might limit their …

Lipid nanovesicles for biomedical applications:'What is in a name'?

AC Apolinário, L Hauschke, JR Nunes… - Progress in lipid research, 2021 - Elsevier
Vesicles, generally defined as self-assembled structures formed by single or multiple
concentric bilayers that surround an aqueous core, have been widely used for biomedical …

The protective effects of melatonin on aluminum‐induced hepatotoxicity and nephrotoxicity in rats

MS Othman, MA Fareid… - Oxidative Medicine …, 2020 - Wiley Online Library
Aluminum (Al) is a ubiquitous element with known toxicity for both humans and animals.
Herein, we aimed to investigate the potential role of melatonin (MEL) in hepatotoxicity and …

Super magnetic niosomal nanocarrier as a new approach for treatment of breast cancer: a case study on SK-BR-3 and MDA-MB-231 cell lines

E Jamshidifar, F Eshrati Yeganeh, M Shayan… - International journal of …, 2021 - mdpi.com
In the present study, a magnetic niosomal nanocarrier for co-delivery of curcumin and
letrozole into breast cancer cells has been designed. The magnetic NiCoFe2O4 core was …

Inflammation, mitochondria and natural compounds together in the circle of trust

S Nesci, A Spagnoletta, F Oppedisano - International Journal of …, 2023 - mdpi.com
Human diseases are characterized by the perpetuation of an inflammatory condition in
which the levels of Reactive Oxygen Species (ROS) are quite high. Excessive ROS …

Nanocurcumin alleviates inflammation and oxidative stress in LPS-induced mastitis via activation of Nrf2 and suppressing TLR4-mediated NF-κB and HMGB1 …

MA Lebda, IH Elmassry, NM Taha… - Environmental Science and …, 2022 - Springer
Coliform mastitis is a worldwide serious disease of the mammary gland. Curcumin is a
pleiotropic polyphenol obtained from turmeric, but it is hydrophobic and rapidly eliminated …

Amelioration of aluminum-induced hepatic and nephrotoxicity by Premna odorata extract is mediated by lowering MMP9 and TGF-β gene alterations in Wistar rat

WMS Ahmed, MA Ibrahim, NA Helmy… - … science and pollution …, 2022 - Springer
This study aims to investigate the effect of Premna odorata (P. odorata)(Lamiaceae) on the
hepatic and nephrotoxicity induced by aluminum chloride (AlCl3) in rat. Wistar male rats …

The protective effect of esculetin against aluminium chloride‐induced reproductive toxicity in rats

E Türk, I Ozan Tekeli, H Özkan, A Uyar, M Cellat… - Andrologia, 2021 - Wiley Online Library
One of the prominent health problems caused by Aluminium was the decrease in male
fertility rates. In the study, the protective effect of Esculetin (ESC) against the reproductive …

Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent

Y Susilawati, AY Chaerunisa… - Journal of Advanced …, 2021 - journals.lww.com
Plants have been used as traditional medicine since ancient times for treating the diseases,
metabolite active compounds from plants have excellent bioactivity, and pharmacological …

Neuroprotective effects of curcumin-loaded nanophytosome on ketamine-induced schizophrenia-like behaviors and oxidative damage in male mice

AH Moghaddam, K Maboudi, B Bavaghar… - Neuroscience …, 2021 - Elsevier
Curcumin as an antioxidant natural herb has shown numerous pharmacological effects.
However, the poor bioavailability of curcumin is a significant pharmacological barrier for its …