Data-independent acquisition mass spectrometry (DIA-MS) is a next generation proteomic
methodology that generates permanent digital proteome maps offering highly reproducible …

Rats and mice are used for studying neuronal circuits underlying recognition memory due to
their ability to spontaneously remember the occurrence of an object, its place and an …

The acute stress response mobilizes energy to meet situational demands and re-establish
homeostasis. However, the underlying molecular cascades are unclear. Here, we use a brief …

Rats and mice have been demonstrated to show episodic-like memory, a prototype of
episodic memory, as defined by an integrated memory of the experience of an object or …

The hippocampus and entorhinal cortex (EC), the earliest affected areas, are considered
relative to early memory loss in Alzheimer's disease (AD). The hippocampus is composed of …

Medial and lateral entorhinal cortices convey spatial/contextual and item/object information
to the hippocampus, respectively. Whether the distinct inputs are integrated as one cognitive …

With advancing age, memory declines through different mechanisms including
dysregulation of expression of synaptic plasticity genes in hippocampus. Increasing …

ABSTRACT SWATH-mass spectrometry (MS) enables accurate and reproducible proteomic
profiling in multiple model organisms including the mouse. Here, we present a …

The hippocampus is well established as an essential brain center for learning and memory.
Within the hippocampus, recent studies show that area CA2 is important for social memory …

Recent studies have suggested that emotional reactivity changes with age, but the neural
basis is still unclear. The insula may be critical for the emotional reactivity. The current study …