Nanomedicine‐boosting tumor immunogenicity for enhanced immunotherapy

J Huang, B Yang, Y Peng, J Huang… - Advanced Functional …, 2021 - Wiley Online Library
Immunotherapy has revolutionized oncology remarkably and gained great improvements in
cancer therapy. However, tumor immunotherapy still encounters serious challenges …

Theranostic nanoparticles with disease-specific administration strategies

P Zhang, Y Li, W Tang, J Zhao, L Jing, KJ McHugh - Nano Today, 2022 - Elsevier
Recent advances in the synthesis of nanomaterials with diagnostic and therapeutic
capabilities have been rapidly reshaping the landscape of precision medicine. Impressive …

Chemical strategies to boost cancer vaccines

WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

Polymeric nanoparticle-based nanovaccines for cancer immunotherapy

Y Zhang, J Chen, L Shi, F Ma - Materials Horizons, 2023 - pubs.rsc.org
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …

Recent advances in biomaterial-boosted adoptive cell therapy

Y Xue, J Che, X Ji, Y Li, J Xie, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Adoptive immunotherapies based on the transfer of functional immune cells hold great
promise in treating a wide range of malignant diseases, especially cancers, autoimmune …

Improving vaccine and immunotherapy design using biomaterials

ML Bookstaver, SJ Tsai, JS Bromberg, CM Jewell - Trends in immunology, 2018 - cell.com
Polymers, lipids, scaffolds, microneedles, and other biomaterials are rapidly emerging as
technologies to improve the efficacy of vaccines against infectious disease and …

Nanovaccine‐based strategies to overcome challenges in the whole vaccination cascade for tumor immunotherapy

L Qin, H Zhang, Y Zhou, CS Umeshappa, H Gao - Small, 2021 - Wiley Online Library
Nanovaccine‐based immunotherapy (NBI) has received greater attention recently for its
potential to prime tumor‐specific immunity and establish a long‐term immune memory that …

Design of polymeric carriers for intracellular peptide delivery in oncology applications

S Lv, M Sylvestre, AN Prossnitz, LF Yang… - Chemical …, 2021 - ACS Publications
In recent decades, peptides, which can possess high potency, excellent selectivity, and low
toxicity, have emerged as promising therapeutics for cancer applications. Combined with an …

Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy

J Jiang, Y Huang, Z Zeng, C Zhao - ACS nano, 2023 - ACS Publications
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …

Photothermal-Activatable Fe3O4 Superparticle Nanodrug Carriers with PD-L1 Immune Checkpoint Blockade for Anti-metastatic Cancer Immunotherapy

R Ge, C Liu, X Zhang, W Wang, B Li, J Liu… - … applied materials & …, 2018 - ACS Publications
Checkpoint blockade immunotherapy has shown great potential in clinical cancer therapy,
but the body's systemic immune must be fully activated and generates a positive tumor …