Defining the Role of Isoeugenol from Ocimum tenuiflorum against Diabetes Mellitus-Linked Alzheimer's Disease through Network Pharmacology and Computational …

RM Martiz, SM Patil, M Abdulaziz, A Babalghith… - Molecules, 2022 - mdpi.com
The present study involves the integrated network pharmacology and phytoinformatics-
based investigation of phytocompounds from Ocimum tenuiflorum against diabetes mellitus …

Discovery of novel coumarin derivatives as potential dual inhibitors against α-glucosidase and α-amylase for the management of post-prandial hyperglycemia via …

SM Patil, RM Martiz, AM Satish, AM Shbeer, M Ageel… - Molecules, 2022 - mdpi.com
Coumarin derivatives are proven for their therapeutic uses in several human diseases and
disorders such as inflammation, neurodegenerative disorders, cancer, fertility, and microbial …

Computer-Aided Screening of Phytoconstituents from Ocimum tenuiflorum against Diabetes Mellitus Targeting DPP4 Inhibition: A Combination of Molecular Docking …

H Sajal, SM Patil, R Raj, AM Shbeer, M Ageel, R Ramu - Molecules, 2022 - mdpi.com
Diabetes mellitus is a major global health concern in the current scenario which is chiefly
characterized by the rise in blood sugar levels or hyperglycemia. In the context, DPP4 …

Integrated network pharmacology and molecular modeling approach for the discovery of novel potential MAPK3 inhibitors from whole green jackfruit flour targeting …

T Maradesha, RM Martiz, SM Patil, A Prasad… - Plos one, 2023 - journals.plos.org
The current study investigates the effectiveness of phytocompounds from the whole green
jackfruit flour methanol extract (JME) against obesity-linked diabetes mellitus using …

[HTML][HTML] Pharmacoinformatics based screening discovers swertianolin from Lavandula angustifolia as a novel neuromodulator targeting epilepsy, depression, and …

SM Patil, KA Al-Mutairi, N Firdose, R Ramu… - South African Journal of …, 2022 - Elsevier
In the present study, we evaluate the pharmacological significance of phytoconstituents
derived from Lavandula angustifolia with respect to anticonvulsant, antidepressant, and …

Novel Pyrazole Acyl (thio) urea Derivatives Containing a Biphenyl Scaffold as Potential Succinate Dehydrogenase Inhibitors: Design, Synthesis, Fungicidal Activity …

NB Sun, LJ Min, XP Sun, ZW Zhai… - Journal of Agricultural …, 2024 - ACS Publications
As part of a program to discover novel succinate dehydrogenase inhibitor fungicides, a
series of new pyrazole acyl (thio) urea compounds containing a diphenyl motif were …

Phyto-Computational Intervention of Diabetes Mellitus at Multiple Stages Using Isoeugenol from Ocimum tenuiflorum: A Combination of Pharmacokinetics and …

RM Martiz, SM Patil, D Thirumalapura Hombegowda… - Molecules, 2022 - mdpi.com
In the present study, the anti-diabetic potential of Ocimum tenuiflorum was investigated
using computational techniques for α-glucosidase, α-amylase, aldose reductase, and …

Molecular insights into the in silico discovery of corilagin from Terminalia chebula as a potential dual inhibitor of SARS-CoV-2 structural proteins

S Pradeep, SM Patil, C Dharmashekara… - Journal of …, 2023 - Taylor & Francis
The spike (S) glycoprotein and nucleocapsid (N) proteins are the crucial pathogenic proteins
of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its …

Multiprotein inhibitory effect of dietary polyphenol rutin from whole green jackfruit flour targeting different stages of diabetes mellitus: defining a bio-computational …

T Maradesha, SM Patil, B Phanindra, RR Achar… - Separations, 2022 - mdpi.com
The anti-diabetic potential of whole unripe jackfruit (peel with pulp, flake, and seed) was
investigated using inhibitory assays for α-glucosidase, α-amylase, aldose reductase, and …

Synthesis, characterization, hirshfeld surface analysis, crystal structure and molecular modeling studies of 1-(4-(Methoxy (phenyl) methyl)-2-methylphenoxy) butan-2 …

C Shivanna, SM Patil, C Mallikarjunaswamy, R Ramu… - Crystals, 2022 - mdpi.com
The crystal compound was synthesized and characterized using conventional analytical
techniques. The compound C19H21O3 crystallizes in a monoclinic crystal system with the …