White matter injury in the preterm infant: pathology and mechanisms

SA Back - Acta neuropathologica, 2017 - Springer
The human preterm brain is particularly susceptible to cerebral white matter injury (WMI) that
disrupts the normal progression of developmental myelination. Advances in the care of …

Pathophysiology of hypoxic–ischemic encephalopathy: a review of the past and a view on the future

P Greco, G Nencini, I Piva, M Scioscia, CA Volta… - Acta Neurologica …, 2020 - Springer
Hypoxic–ischemic encephalopathy, also referred as HIE, is a type of brain injury or damage
that is caused by a lack of oxygen to the brain during neonatal period. The incidence is …

Trial of erythropoietin for hypoxic–ischemic encephalopathy in newborns

YW Wu, BA Comstock, FF Gonzalez… - New England journal …, 2022 - Mass Medical Soc
Background Neonatal hypoxic–ischemic encephalopathy is an important cause of death as
well as long-term disability in survivors. Erythropoietin has been hypothesized to have …

Neurodevelopmental abnormalities in children with in utero Zika virus exposure without congenital Zika syndrome

SB Mulkey, M Arroyave-Wessel, C Peyton… - JAMA …, 2020 - jamanetwork.com
Importance The number of children who were born to mothers with Zika virus (ZIKV) infection
during pregnancy but who did not have apparent disability at birth is large, warranting the …

Management and investigation of neonatal encephalopathy: 2017 update

K Martinello, AR Hart, S Yap, S Mitra… - Archives of Disease in …, 2017 - fn.bmj.com
This review discusses an approach to determining the cause of neonatal encephalopathy,
as well as current evidence on resuscitation and subsequent management of hypoxic …

Current and emerging therapies in the management of hypoxic ischemic encephalopathy in neonates

J Nair, VHS Kumar - Children, 2018 - mdpi.com
Neonatal hypoxic ischemic encephalopathy (HIE) presents a significant clinical burden with
its high mortality and morbidity rates globally. Therapeutic hypothermia (TH) is now standard …

Perinatal brain injury: mechanisms, prevention, and outcomes

CM Novak, M Ozen, I Burd - Clinics in perinatology, 2018 - perinatology.theclinics.com
Perinatal Brain Injury - Clinics in Perinatology Skip to Main Content Clinics in Perinatology
Log in Register Log in Subscribe Claim Skip menu theclinics.com theclinics.com External Link …

New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy

S Victor, E Rocha-Ferreira, A Rahim, H Hagberg… - European journal of …, 2022 - Springer
Around 0.75 million babies worldwide suffer from moderate or severe hypoxic-ischemic
encephalopathy (HIE) each year resulting in around 400,000 babies with …

Neuroimaging in the term newborn with neonatal encephalopathy

JL Wisnowski, P Wintermark, SL Bonifacio… - Seminars in Fetal and …, 2021 - Elsevier
Neuroimaging is widely used to aid in the diagnosis and clinical management of neonates
with neonatal encephalopathy (NE). Yet, despite widespread use clinically, there are few …

Plasma biomarkers of brain injury in neonatal hypoxic-ischemic encephalopathy

AN Massaro, YW Wu, TK Bammler, B Comstock… - The Journal of …, 2018 - Elsevier
Objectives To evaluate plasma brain specific proteins and cytokines as biomarkers of brain
injury in newborns with hypoxic-ischemic encephalopathy (HIE) and, secondarily, to assess …