The landscape of infectious fungal agents includes previously unidentified or rare
pathogens with the potential to cause unprecedented casualties in biodiversity, food …

The human pathogenic fungus Cryptococcus neoformans is a global health concern.
Previous research in the field has focused on studies using reference strains to identify …

Cryptococcus neoformans is a major human central nervous system (CNS) fungal pathogen
causing considerable morbidity and mortality. In this study, we provide the widest view to …

Fungi often adapt to environmental stress by altering their size, shape, or rate of cell division.
These morphological changes require reorganization of the cell wall, a structural feature …

Meningitis due to the fungal pathogen Cryptococcus neoformans is estimated to cause
nearly 200,000 deaths annually, mostly in resource-limited regions. We previously identified …

Long non-coding RNAs (lncRNAs) are highly expressed and can modulate multiple cellular
processes including transcription, splicing, translation, and many diverse signaling events …

In exploring the evolutionary trajectories of both pathogenesis and karyotype dynamics in
fungi, we conducted a large-scale comparative genomic analysis spanning the …

Evaluating the quality of a de novo annotation of a complex fungal genome based on RNA-
seq data remains a challenge. In this study, we sequentially optimized a Cufflinks …

The “Amoeboid Predator-Fungal Animal Virulence Hypothesis” posits that interactions with
environmental phagocytes shape the evolution of virulence traits in fungal pathogens. In this …

Cryptococcus neoformans is a facultative intracellular pathogen that can replicate and
disseminate in mammalian macrophages. In this study, we analyzed fungal proteins …