Frailty and cancer: implications for oncology surgery, medical oncology, and radiation oncology

CG Ethun, MA Bilen, AB Jani, SK Maithel… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE The concept of frailty has become increasingly
recognized as one of the most important issues in health care and health outcomes and is of …

Bladder cancer, inflammageing and microbiomes

A Martin, BL Woolbright, S Umar, MA Ingersoll… - Nature Reviews …, 2022 - nature.com
Ageing is correlated with elevated bladder cancer incidence, morbidity and mortality.
Advanced age is also associated with elevated markers of chronic inflammation and …

The association of frailty with outcomes after cancer surgery: a systematic review and metaanalysis

JF Shaw, D Budiansky, F Sharif, DI McIsaac - Annals of Surgical Oncology, 2022 - Springer
Background Cancer is common in older adults, who often have concurrent frailty. Frailty is a
strong predictor of adverse outcomes in surgical patients. Our objective is to systematically …

Multimodal prehabilitation to enhance functional capacity following radical cystectomy: a randomized controlled trial

EM Minnella, R Awasthi, G Bousquet-Dion… - European urology …, 2021 - Elsevier
Background In patients with bladder cancer, poor functional status has remarkable
deleterious effects on postoperative outcome and prognosis. Conditioning intervention …

Frailty index developed from a cancer-specific geriatric assessment and the association with mortality among older adults with cancer

EJ Guerard, AM Deal, YK Chang, GR Williams… - Journal of the National …, 2017 - jnccn.org
Background: An objective measure is needed to identify frail older adults with cancer who
are at increased risk for poor health outcomes. The primary objective of this study was to …

[HTML][HTML] Modified frailty index predicts morbidity and mortality after pancreaticoduodenectomy

H Mogal, SA Vermilion, R Dodson, FC Hsu… - Annals of surgical …, 2017 - Springer
Background Pancreatic cancer is a disease of older adults, who may present with limited
physiologic reserve. The authors hypothesized that a frailty index can predict postoperative …

[HTML][HTML] Advanced bladder cancer: Changing the treatment landscape

V Bilim, H Kuroki, Y Shirono, M Murata… - Journal of Personalized …, 2022 - mdpi.com
Bladder cancer is the 10th most common cancer type in the world. There were more than
573,000 new cases of bladder cancer in 2020. It is the 13th most common cause of cancer …

Modified frailty index predicts postoperative outcomes in older gastrointestinal cancer patients

SA Vermillion, FC Hsu, RD Dorrell… - Journal of surgical …, 2017 - Wiley Online Library
Background and Objectives Frailty disproportionately impacts older patients with
gastrointestinal cancer, rendering them at increased risk for poor outcomes. A frailty index …

Frailty as a predictor of complications after radical cystectomy: a prospective study of various preoperative assessments

ML Burg, TG Clifford, ST Bazargani… - … Oncology: Seminars and …, 2019 - Elsevier
Purpose Frailty has been correlated with worse postoperative outcomes. Prospective studies
examining frailty and bladder cancer are lacking. We aimed to determine whether a …

Patient frailty predicts worse perioperative outcomes and higher cost after radical cystectomy

C Palumbo, S Knipper, A Pecoraro, G Rosiello… - Surgical oncology, 2020 - Elsevier
Background: Relatively few studies investigated the importance of frailty in radical
cystectomy (RC) patients. We tested the ability of frailty, using the Johns Hopkins Adjusted …