As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …

Telomeres play an important part in aging and show relationships to lifetime adversity,
particularly childhood adversity. Meta-analyses demonstrate reliable associations between …

Major depressive disorder (MDD) is associated with an increased risk of brain atrophy,
aging-related diseases, and mortality. We examined potential advanced brain aging in adult …

Importance Many children and adolescents in the United States are exposed to
neighborhood gun violence. Associations between violence exposure and children's short …

Background Studies often evaluate mental health and well-being in association with
individual health behaviours although evaluating multiple health behaviours that co-occur in …

Biological clocks have been developed at different molecular levels and were found to be
more advanced in the presence of somatic illness and mental disorders. However, it is …

DNA methylation patterns at specific cytosine-phosphate-guanine (CpG) sites predictably
change with age and can be used to derive “epigenetic age”, an indicator of biological age …

Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …

Different psychiatric disorders as well as exposure to adverse life events have individually
been associated with multiple age-related diseases and mortality. Age acceleration in …

Background Biological processes of aging are thought to be modifiable causes of many
different chronic diseases. Measures of biological aging could provide sensitive endpoints …