The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus

SM Robert, BC Reeves, E Kiziltug, PQ Duy, JK Karimy… - Cell, 2023 - cell.com
The choroid plexus (ChP) is the blood-cerebrospinal fluid (CSF) barrier and the primary
source of CSF. Acquired hydrocephalus, caused by brain infection or hemorrhage, lacks …

Choroid plexus enlargement in inflammatory multiple sclerosis: 3.0-T MRI and translocator protein PET evaluation

VAG Ricigliano, E Morena, A Colombi, M Tonietto… - Radiology, 2021 - pubs.rsna.org
Background Choroid plexuses (CPs) have been suggested as a key gateway for
inflammation in experimental autoimmune encephalitis, but in vivo evidence of their …

A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies

J Brasanac, C Chien - Frontiers in Human Neuroscience, 2023 - frontiersin.org
Magnetic resonance imaging (MRI) of the brain is commonly used to detect where chronic
and active lesions are in multiple sclerosis (MS). MRI is also extensively used as a tool to …

The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis

I Lazarevic, S Soldati, JA Mapunda, H Rudolph… - Fluids and Barriers of …, 2023 - Springer
The choroid plexus (ChP) has been suggested as an alternative central nervous system
(CNS) entry site for CCR6+ Th17 cells during the initiation of experimental autoimmune …

Choroid plexus volume in multiple sclerosis vs neuromyelitis optica spectrum disorder: a retrospective, cross-sectional analysis

J Müller, T Sinnecker, MJ Wendebourg… - Neurology …, 2022 - AAN Enterprises
Background and Objectives The choroid plexus has been shown to play a crucial role in
CNS inflammation. Previous studies found larger choroid plexus in multiple sclerosis (MS) …

Association of choroid plexus inflammation on MRI with clinical disability progression over 5 years in patients with multiple sclerosis

N Bergsland, MG Dwyer, D Jakimovski, E Tavazzi… - Neurology, 2023 - AAN Enterprises
Background and Objectives Inflammation of the choroid plexus (CP) has been reported in
multiple sclerosis (MS). The AU1 association between CP inflammation and clinical …

A fully automatic method to segment choroid plexuses in multiple sclerosis using conventional MRI sequences

L Storelli, E Pagani, M Rubin, M Margoni… - Journal of Magnetic …, 2024 - Wiley Online Library
Background Choroid plexus (CP) volume has been recently proposed as a proxy for brain
neuroinflammation in multiple sclerosis (MS). Purpose To develop and validate a fast …

[HTML][HTML] Application of contrast-enhanced magnetic resonance imaging in the assessment of blood-cerebrospinal fluid barrier integrity

ICM Verheggen, WM Freeze, JJA de Jong… - Neuroscience & …, 2021 - Elsevier
Abstract VERHEGGEN, ICM, W. Freeze, J. de Jong, J. Jansen, A. Postma, M. van Boxtel, F.
Verhey and W. Backes. The application of contrast-enhanced MRI in the assessment of …

Choroid plexus volume change—A candidate for a new radiological marker of MS progression

A Jankowska, K Chwojnicki, M Grzywińska… - Diagnostics, 2023 - mdpi.com
(1) Background: Multiple sclerosis (MS) is an auto-immune, chronic, neuroinflammatory,
demyelinating disease that affects mainly young patients. This progressive inflammatory …

Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis

R Magliozzi, S Hametner, M Mastantuono… - Brain …, 2024 - Wiley Online Library
Among the intrathecal inflammatory niches where compartmentalized inflammation persists
and plays a pivotal role in progressive multiple sclerosis (MS), choroid plexus (CP) has …