Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Polysaccharides have attracted considerable attention in a broad range of applications in
recent years, which is due to their remarkable features such as biocompatibility …

Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …

Purpose To review the current therapeutic options for the management of diabetic
retinopathy (DR) and diabetic macular edema (DME) and examine the evidence for …

As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues,
hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry …

Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …

There is an increasing momentum in research and pharmaceutical industry communities to
design sustained, non-invasive delivery systems to treat chronic neovascular ocular …

Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as
polysaccharide derivatives, have been successfully used to augment drug delivery in the …

Ocular drug delivery has seen several advances in the past few decades, with respect to
new drugs, improved formulations, targeted delivery, as well as exploration of new routes of …